Protein Alignment Sox21a and Sox2

DIOPT Version :9

• Sequence 1: NP_001261827.1
• Gene: Sox21a / 39567
• FlyBaseID: FBgn0036411
• Length: 407
• Species: Drosophila melanogaster
• Sequence 2: NP_035573.3
• Gene: Sox2 / 20674
• MGIID: 98364
• Length: 319
• Species: Mus musculus
• Alignment Length: 339
• Identity: 134/339 - (39%)
• Similarity: 160/339 - (47%)
• Gaps: 84/339 - (24%)

  Fly    82 TPVAPKMHQHTHHHGNSHHNAPTSHSNSNTGSHHNSHDHIKRPMNAFMVWSRGQRRKMAQDNPKM 146
            |.:.|...|.....|....||..:   :..|:..||.|.:||||||||||||||||||||:||||
Mouse     7 TELKPPGPQQASGGGGGGGNATAA---ATGGNQKNSPDRVKRPMNAFMVWSRGQRRKMAQENPKM 68

  Fly   147 HNSEISKRLGAEWKLLTEGQKRPFIDEAKRLRALHMKEHPDYKYRPRRKPKTL---NKSPVPGG- 207
            ||||||||||||||||:|.:|||||||||||||||||||||||||||||.|||   :|..:|||
Mouse    69 HNSEISKRLGAEWKLLSETEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLMKKDKYTLPGGL 133

  Fly   208 ---------GGGGGGGGANGGVNAGGAGNSGPSGPGSVGSPKDMQPQLSPLGQSLPHLHGHPHQS 263
                     .|.|.|.|...|||......:..:| .|.||...||.||
Mouse   134 LAPGGNSMASGVGVGAGLGAGVNQRMDSYAHMNG-WSNGSYSMMQEQL----------------- 180

  Fly   264 PYQSHPHHP--HPH------PHH------VQLAAATLSAKYGFGSPLELSLPRLPNAFPGLAHYP 314
               .:|.||  :.|      |.|      :|..:.|.|..|..||| ..|:.......||:|
Mouse   181 ---GYPQHPGLNAHGAAQMQPMHRYDVSALQYNSMTSSQTYMNGSP-TYSMSYSQQGTPGMA--- 238

  Fly   315 LDPTLALDLQARLQAMYAGSIYHPWRYLPLISPETPPSPPSSSGTGISSYGCVKSEKSS------ 373
                        |.:|  ||:         :..|...|||..:.:..|...|...:...
Mouse   239 ------------LGSM--GSV---------VKSEASSSPPVVTSSSHSRAPCQAGDLRDMISMYL 280

  Fly   374 PNAVVASAASPPNI 387
            |.|.|...|:|..:
Mouse   281 PGAEVPEPAAPSRL 294

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox21a	NP_001261827.1	SOX-TCF_HMG-box	120..191	CDD:238684	64/70 (91%)
Sox2	NP_035573.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..43		10/38 (26%)
		SOX-TCF_HMG-box	42..113	CDD:238684	64/70 (91%)
		SOXp	112..202	CDD:403523	34/110 (31%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	247..267		5/19 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	299..319

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167838609
Domainoid	1	1.000	139	1.000	Domainoid score	I4760
eggNOG	1	0.900	-	-		E1_KOG0527
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	180	1.000	Inparanoid score	I3991
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000028
OrthoInspector	1	1.000	-	-		otm43964
orthoMCL	1	0.900	-	-		OOG6_106862
Panther	1	1.100	-	-	O	PTHR10270
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	9.790