Protein Alignment Sox21a and sem-2

DIOPT Version :9

• Sequence 1: NP_001261827.1
• Gene: Sox21a / 39567
• FlyBaseID: FBgn0036411
• Length: 407
• Species: Drosophila melanogaster
• Sequence 2: NP_740846.1
• Gene: sem-2 / 172162
• WormBaseID: WBGene00004771
• Length: 404
• Species: Caenorhabditis elegans
• Alignment Length: 408
• Identity: 118/408 - (28%)
• Similarity: 161/408 - (39%)
• Gaps: 146/408 - (35%)

  Fly    66 PPPMPP---ADLAVPPAAPTPVAPK--------MHQHTHHH------GNSHH------NAPTSHS 107
            |..|||   |..|:..|:.|..|..        ..|...||      |...|      .:.|.:|
 Worm    17 PHMMPPINWAAAAIAVASSTSGATNATSSNSVATSQQLQHHPYGTAAGGYKHAQQAIPKSVTPYS 81

  Fly   108 NSNTGSHHNSHDHIKRPMNAFMVWSRGQRRKMAQDNPKMHNSEISKRLGAEWKLLTEGQKRPFID 172
            ::.  :...|.:|||||||||||||:.:|||:.:..|.|||:||||:||:.|:.||:.:|.||:.
 Worm    82 DAT--NCKKSSNHIKRPMNAFMVWSQMERRKICEHQPDMHNAEISKQLGSRWRSLTDEEKAPFVA 144

  Fly   173 EAKRLRALHMKEHPDYKYRPRRKPKTLNKSPVPGGGGGGGGGGANGGVNAGGAGNSGPSG----P 233
            ||:|||..||:|:|||||:||:|||                              ..|.|    |
 Worm   145 EAERLRVCHMQEYPDYKYKPRKKPK------------------------------KNPDGTLQQP 179

  Fly   234 GSVGSPKDMQPQLSPLGQSLPHLH-----------------------------GHPHQSPYQSHP 269
            ....:|:  |.|..|.|.| |...                             |:.|.|..|..|
 Worm   180 AQPQAPQ--QQQAPPRGAS-PQARQRKRPNTDQQSETQQFQNFKSVKVEQDWMGNAHMSHAQKMP 241

  Fly   270 HHP-HPHPHHVQLAAATLSAKYGF----------------------GSPLELSLPRLPNAFPGLA 311
            .|| :|.|.  :...|.|:.:.||                      ||||.::
 Worm   242 FHPSYPSPS--EFGHAPLTPESGFYDDYFTQQHHQQHFASQHHNSAGSPLRMT------------ 292

  Fly   312 HYPLDPTLALDLQARLQAMYAGSIY----HPWRYLPLISPETPPSPPSSSGTGISSYG-CVKSEK 371
                  .|.:|:....|.|...|.:    ||: ||....|........|..:|.|.|. |..||:
 Worm   293 ------NLGMDMGMPPQMMGHNSGFGAGNHPF-YLHTSPPSVDQDDMRSLSSGSSGYADCSASEQ 350

  Fly   372 --SSPNA----VVASAAS 383
              ||||:    .:|:||:
 Worm   351 STSSPNSAGVVTMATAAT 368

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox21a	NP_001261827.1	SOX-TCF_HMG-box	120..191	CDD:238684	44/70 (63%)
sem-2	NP_740846.1	SOX-TCF_HMG-box	92..159	CDD:238684	40/66 (61%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0527
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	136	1.000	Inparanoid score	I3128
Isobase	1	0.950	-	0	Normalized mean entropy	S1275
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000028
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10270
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R685
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.940