DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sox21a and sox32

DIOPT Version :9

Sequence 1:	NP_001261827.1	Gene:	Sox21a / 39567	FlyBaseID:	FBgn0036411	Length:	407	Species:	Drosophila melanogaster
Sequence 2:	NP_571926.1	Gene:	sox32 / 116990	ZFINID:	ZDB-GENE-011026-1	Length:	307	Species:	Danio rerio

Alignment Length:	230	Identity:	58/230 - (25%)
Similarity:	103/230 - (44%)	Gaps:	38/230 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    89 HQHTHHHGNSHHNAPTSHSNSNTGSHHNS---------HDHIKRPMNAFMVWSRGQRRKMAQDNP 144
            ||:......:|..|....|..:.||..:.         ...::||:|||::|::.:||::||.||
Zfish    29 HQNDEQRRTAHCPASGPLSPVSVGSESSCSSPEAKAPVETRVRRPLNAFIIWTKEERRRLAQLNP 93

  Fly   145 KMHNSEISKRLGAEWKLLTEGQKRPFIDEAKRLRALHMKEHPDYKYRPRRKPKTLNKSPVPGGGG 209
            .:.|:::||.||..||.::...|||::.||:|||..|..::|:|||||||:......|.:|..
Zfish    94 DLENTDLSKILGKTWKAMSLADKRPYMQEAERLRIQHTIDYPNYKYRPRRRKCNKRSSKMPSS-- 156

  Fly   210 GGGGGGANGGVNAGGAGNSGPSGPGSVGSPK---DMQPQLSPLGQSLPHLHGHPHQSPYQSHPHH 271
                                    .:|.||.   |:...........|:...:.::.|:......
Zfish   157 ------------------------ENVSSPNATFDLSYMFQGQAPQRPYNQINSYRLPHNGFSFE 197

  Fly   272 PHPHPHHVQLAAATLSAKYGFGSPLELSLPRLPNA 306
            .|...:|.:..:::.:..:|..:.:.||...||.:
Zfish   198 NHSSSYHFEATSSSGNVFHGGATSMNLSNVHLPRS 232

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sox21a	NP_001261827.1	SOX-TCF_HMG-box	120..191	CDD:238684	31/70 (44%)
sox32	NP_571926.1	SOX-TCF_HMG-box	69..140	CDD:238684	31/70 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170582327
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000028
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10270
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.940