Protein Alignment Sox21a and SOX21

DIOPT Version :9

• Sequence 1: NP_001261827.1
• Gene: Sox21a / 39567
• FlyBaseID: FBgn0036411
• Length: 407
• Species: Drosophila melanogaster
• Sequence 2: NP_009015.1
• Gene: SOX21 / 11166
• HGNCID: 11197
• Length: 276
• Species: Homo sapiens
• Alignment Length: 290
• Identity: 116/290 - (40%)
• Similarity: 133/290 - (45%)
• Gaps: 92/290 - (31%)

  Fly   119 DHIKRPMNAFMVWSRGQRRKMAQDNPKMHNSEISKRLGAEWKLLTEGQKRPFIDEAKRLRALHMK 183
            ||:||||||||||||.|||||||:||||||||||||||||||||||.:|||||||||||||:|||
Human     6 DHVKRPMNAFMVWSRAQRRKMAQENPKMHNSEISKRLGAEWKLLTESEKRPFIDEAKRLRAMHMK 70

  Fly   184 EHPDYKYRPRRKPKTLNKS-----PVPGGGGG-----------GGG--GGANGGV---------- 220
            ||||||||||||||||.|.     |||.|.||           |.|  .||.||:
Human    71 EHPDYKYRPRRKPKTLLKKDKFAFPVPYGLGGVADAEHPALKAGAGLHAGAGGGLVPESLLANPE 135

  Fly   221 ---------------NAGGAGNSGPSGPGSVGSPKDMQPQLSPLGQSLPHLHGHPHQSPYQS--- 267
                           ....|..:..:...:.|||.    .|..||..:..:.......||.|
Human   136 KAAAAAAAAAARVFFPQSAAAAAAAAAAAAAGSPY----SLLDLGSKMAEISSSSSGLPYASSLG 196

  Fly   268 -------------------------HPH-HPHP-HPHHVQLAAATLSAKYGFGSPLELSLPRLPN 305
                                     |.| ||.| :|.::.....:.....|...||...|
Human   197 YPTAGAGAFHGAAAAAAAAAAAAGGHTHSHPSPGNPGYMIPCNCSAWPSPGLQPPLAYIL----- 256

  Fly   306 AFPGLAHYPLDPTLALDLQARLQAMYAGSI 335
             .||:....|||         ..|.||.::
Human   257 -LPGMGKPQLDP---------YPAAYAAAL 276

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox21a	NP_001261827.1	SOX-TCF_HMG-box	120..191	CDD:238684	64/70 (91%)
SOX21	NP_009015.1	SOX-TCF_HMG-box	7..78	CDD:238684	64/70 (91%)
		SOXp	77..>95	CDD:403523	11/17 (65%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	139	1.000	Domainoid score	I4785
eggNOG	1	0.900	-	-		E1_KOG0527
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000028
OrthoInspector	1	1.000	-	-		otm41916
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10270
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R685
SonicParanoid	1	1.000	-	-		X1501
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	9	8.900