DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sox21a and sox15

DIOPT Version :9

Sequence 1:	NP_001261827.1	Gene:	Sox21a / 39567	FlyBaseID:	FBgn0036411	Length:	407	Species:	Drosophila melanogaster
Sequence 2:	NP_001120046.1	Gene:	sox15 / 100145022	XenbaseID:	XB-GENE-6455809	Length:	199	Species:	Xenopus tropicalis

Alignment Length:	232	Identity:	81/232 - (34%)
Similarity:	105/232 - (45%)	Gaps:	69/232 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    69 MPPADLAVPPAAPTPVAPKMHQHTHHHGNSHHNAPTSHSNSNTGSHHNSHDHIKRPMNAFMVWSR 133
            |.|...:.|||.|.|                               .|....:|||||||||||.
Frog     1 MHPPQHSAPPAPPAP-------------------------------PNESPLVKRPMNAFMVWSS 34

  Fly   134 GQRRKMAQDNPKMHNSEISKRLGAEWKLLTEGQKRPFIDEAKRLRALHMKEHPDYKYRPRRK--- 195
            |:|::|:..:|||||||||:|||..|:.|.|.::|||.:|||||||.|..::|.|||.||:|
Frog    35 GERKRMSARHPKMHNSEISRRLGEIWRGLGEDERRPFREEAKRLRAQHAIDYPGYKYAPRKKRKE 99

  Fly   196 ----PKTLNKSPVPGGGGGGGGGGANGGVNAGGAGNSGPSGPGSVGSPKDMQPQLSPLGQSLPHL 256
                ||...::|:                         |..||| ..|:|  |||.|   ..|..
Frog   100 RGEPPKVAPQAPL-------------------------PCPPGS-SPPRD--PQLHP---PPPPT 133

  Fly   257 HGHPHQSPYQSHPHHPHPHPHHVQLAAATLSAKYGFG 293
            |.:..|..|...|:...|.|.....:.:.:||.||||
Frog   134 HYNGFQDGYGYLPYPCPPRPEPFLPSVSDVSALYGFG 170

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sox21a	NP_001261827.1	SOX-TCF_HMG-box	120..191	CDD:238684	43/70 (61%)
sox15	NP_001120046.1	SOX-TCF_HMG-box	22..91	CDD:238684	42/68 (62%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000028
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000