DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sox21a and sox17b.2

DIOPT Version :9

Sequence 1:	NP_001261827.1	Gene:	Sox21a / 39567	FlyBaseID:	FBgn0036411	Length:	407	Species:	Drosophila melanogaster
Sequence 2:	NP_001090837.1	Gene:	sox17b.2 / 100038235	XenbaseID:	XB-GENE-495335	Length:	351	Species:	Xenopus tropicalis

Alignment Length:	179	Identity:	68/179 - (37%)
Similarity:	96/179 - (53%)	Gaps:	11/179 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   101 NAPTSHSNSNTGSHHNSHDHIKRPMNAFMVWSRGQRRKMAQDNPKMHNSEISKRLGAEWKLLTEG 165
            :|.|.....:..|...:...|:|||||||||::.:|:::||.||.:||:|:||.||..||.||..
Frog    16 DAKTKKEAGSANSRGKAEARIRRPMNAFMVWAKDERKRLAQQNPDLHNAELSKMLGKSWKSLTLA 80

  Fly   166 QKRPFIDEAKRLRALHMKEHPDYKYRPRRKPKT-------LNKSPVPGGG--GGGGGGGANGGVN 221
            .||||:.||:|||..|::::||||||||||.:.       |..:.:||..  |.....|.|..:.
Frog    81 SKRPFVKEAERLRVQHIQDYPDYKYRPRRKKQVKREEEGFLPSADIPGPQVMGCNAMVGQNYKMQ 145

  Fly   222 AGGAGNSGPSGPGSVGSPKDMQP-QLSPLGQSLPHLHGHPHQSPYQSHP 269
            ..|. ||..|.....|..:|..| .....|.::|..:...:.|.|.|.|
Frog   146 YSGQ-NSQQSQITPAGYFEDHNPVGFYYRGYNVPKYYMSQNSSGYCSPP 193

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sox21a	NP_001261827.1	SOX-TCF_HMG-box	120..191	CDD:238684	40/70 (57%)
sox17b.2	NP_001090837.1	SOX-TCF_HMG-box	35..106	CDD:238684	40/70 (57%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000028
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10270
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R685
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.040