DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Fbp1 and PPO2

DIOPT Version :9

Sequence 1:	NP_524065.1	Gene:	Fbp1 / 39566	FlyBaseID:	FBgn0000639	Length:	1029	Species:	Drosophila melanogaster
Sequence 2:	NP_610443.1	Gene:	PPO2 / 35910	FlyBaseID:	FBgn0033367	Length:	684	Species:	Drosophila melanogaster

Alignment Length:	490	Identity:	124/490 - (25%)
Similarity:	196/490 - (40%)	Gaps:	112/490 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   612 NRLSEIVLHNLRQLVARLNQE-----------------SIAQGQLIEEQQQLINNPR---LTQSE 656
            :|..|:..:..:|::||.|.|                 .||:|..          |:   |..|.
  Fly   228 DRRGELFYYMHQQVIARYNAERFSNNLARVLPFNNLRDPIAEGYF----------PKMDSLVASR 282

  Fly   657 RYALRLNQIRIN--SQRSRQVLAQIGQIEQ---RIQEVIGQVLNQVNVNSLRGQVIDQR------ 710
            .:..|....|::  ::.|.|:..:||.:|:   ||.|.|.|           |.|:|:|
  Fly   283 AWPPRFESTRLSDLNRESDQLNVEIGDLERWRDRIYEAIHQ-----------GFVMDERGNRVPL 336

  Fly   711 -----------QVESLIAD---VLLGRLGQVGIMTIIRQVVQDNNIEQIDRTG----LGIRLSDP 757
                       .:||.|..   ||.|.|...|...|  ....|...:.::..|    :...:.||
  Fly   337 DEATGIDTLGNMIESSILSPNRVLYGDLHNNGHTFI--SYAHDPTSKHLESFGVMGDVSTAMRDP 399

  Fly   758 VVQYTLRRIVRIVDEQREQILGGYRQEQLQMRGVSINDVRVD-------KLRTRIEEHELDLSNL 815
            |.......|.||..|.:.: |..|.:.||...||||..::||       .|.|..::.::|:|..
  Fly   400 VFYKWHSYIDRIFQEHKSR-LPAYTENQLNYPGVSIAGIQVDTNGGRPNNLTTFWQQSDVDMSRG 463

  Fly   816 VEQQVQGIQQEIVGRQRRLNNKAFTIDMDITSDQ--DQDAIIRIFLGPAEDQQGRQGASLDERRR 878
            .:...:|   .:..|...|.:..||..:.:.:|.  .:...:|||:.|..|::| |...:.::|.
  Fly   464 FDFLPRG---NVFARFTHLQHLPFTYTISLNNDSGAQRFGYVRIFMAPKNDERG-QPMLMRDQRS 524

  Fly   879 DFVLLDAIQVQLENGRNRIHRRSIDIPWTTSDVT-PLVEIYRQVMLQLKGQQAQQVVGIQQLVGE 942
            ..:.||.....|..|.|.|.|||     |.|.|| |....:|.:      ...:...|..:.:..
  Fly   525 MMIELDKFVTSLNPGPNTIRRRS-----TESSVTIPFERTFRNL------DANRPAAGTPEELEF 578

  Fly   943 N----GRFPQHLLLPRGRPEGLPMQLLVVVSPLVELQV-QDVV-----PAITIGIGSASLRDARP 997
            |    | :|.|:|:|:|.||||...|.::||.....:: |.:|     .|...|:......|.:.
  Fly   579 NFCGCG-WPNHMLVPKGLPEGLQCVLFIMVSNYENDRIDQQLVGRCSDAASYCGVRDRLYPDRQS 642

  Fly   998 LGYPLDR-PIHNEQELLQ-LT-NVLLQDVVIIQEN 1029
            :|:|.|| |......|:. || |:.:.||.|..||
  Fly   643 MGFPFDRLPRSGVDRLVNFLTPNMSIVDVNIRHEN 677

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fbp1	NP_524065.1	Hemocyanin_N	38..159	CDD:281684
Fbp1	NP_524065.1	Hemocyanin_C	781..1025	CDD:281685	73/266 (27%)
PPO2	NP_610443.1	Hemocyanin_N	19..140	CDD:281684
		Hemocyanin_M	150..412	CDD:278784	45/206 (22%)
		Hemocyanin_C	421..675	CDD:281685	74/269 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45470673
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11511
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940