DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment btl and SKM1

DIOPT Version :9

Sequence 1:	NP_001014583.1	Gene:	btl / 39564	FlyBaseID:	FBgn0285896	Length:	1052	Species:	Drosophila melanogaster
Sequence 2:	NP_014528.1	Gene:	SKM1 / 854036	SGDID:	S000005473	Length:	655	Species:	Saccharomyces cerevisiae

Alignment Length:	309	Identity:	83/309 - (26%)
Similarity:	141/309 - (45%)	Gaps:	42/309 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   701 LDSNWEIPRQQLSLGSILGEGAFGRVVMAEAEGLPR--SPQLAET--------IVAVKMVK-EEH 754
            :|.|   ||....|....|:||.|.|.:::...||:  .|:..::        .||:|.:: .|.
Yeast   352 IDVN---PRPYFQLVEKAGQGASGAVYLSKRIKLPQENDPRFLKSHCHRVVGERVAIKQIRLSEQ 413

  Fly   755 TDTDMASLVREMEVMKMIGKHINIINLL-GCCSQGGPLWVIVEYAPHGNLKDFLKQNRPGAPQRR 818
            ....:  ::.|:.||. ..:..||:|.| ........||||:||...|.|.|.|     .|..|.
Yeast   414 PKKQL--IMNELLVMN-DSRQENIVNFLEAYIIDDEELWVIMEYMEGGCLTDIL-----DAVARS 470

  Fly   819 SDSDGYLDDKPLISTQHLGEKELTKFAFQIARGMEYLASRRCIHRDLAARNVLVSDGYVMKIADF 883
            :..:         .:..|.|.::.....:..:|:::|.:::.||||:.:.|:|::...::||.||
Yeast   471 NTGE---------HSSPLNENQMAYIVKETCQGLKFLHNKKIIHRDIKSDNILLNSQGLVKITDF 526

  Fly   884 GLARDIQDTEYYRKNTNGRLPIKWMAPESLQEKKYDSQSDVWSYGVLLWEIMTYGDQPYPHILSA 948
            |...::.:....|....| .|. |||||.:.:|.||.:.||||.|::|.| |..|:.||   |:.
Yeast   527 GFCVELTEKRSKRATMVG-TPY-WMAPEIVNQKGYDEKVDVWSLGIMLIE-MIEGEPPY---LNE 585

  Fly   949 EELYS-YLITGQ---RMEKPAKCSLNIYVVMRQCWHFESCARPTFAELV 993
            :.|.: |||...   ::..|...|......:..|......:|.:..:|:
Yeast   586 DPLKALYLIANNGSPKLRHPESVSKQTKQFLDACLQVNVESRASVRKLL 634

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
btl	NP_001014583.1	IG_like	149..232	CDD:214653
		IGc2	157..215	CDD:197706
		IG	247..336	CDD:214652
		Ig	258..340	CDD:143165
		I-set	394..479	CDD:254352
		IGc2	408..469	CDD:197706
		IG_like	492..583	CDD:214653
		Ig	507..583	CDD:299845
		PKc_like	700..1000	CDD:304357	83/309 (27%)
		TyrKc	712..996	CDD:197581	79/298 (27%)
SKM1	NP_014528.1	PH_Cla4_Ste20	4..113	CDD:270097
		PBD	122..180	CDD:395634
		STKc_PAK	359..640	CDD:270789	79/299 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000