DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment btl and AT5G48740

DIOPT Version :9

Sequence 1:	NP_001014583.1	Gene:	btl / 39564	FlyBaseID:	FBgn0285896	Length:	1052	Species:	Drosophila melanogaster
Sequence 2:	NP_199685.2	Gene:	AT5G48740 / 834932	AraportID:	AT5G48740	Length:	895	Species:	Arabidopsis thaliana

Alignment Length:	1022	Identity:	219/1022 - (21%)
Similarity:	350/1022 - (34%)	Gaps:	333/1022 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   158 GLFQLNCSPMDPDAKGVNISWL-HNDTQILGGRGRIKLKRWSLTVG---QLQPEDAGSYHCELCV 218
            |...|:|......| ..||||: .||....|....:.....:.|..   :|.|:..|....:|.|
plant    20 GFLSLSCGGSSYTA-AYNISWVSDNDYIETGNTTTVTYAEGNSTSSVPIRLFPDPQGRQCYKLPV 83

  Fly   219 EQ----------------DCQRSNPTQLEVISRKHTVPM-LKPGYP---------RNTSIALGDN 257
            .:                |.|.|.|.....:.|:.|..: |:...|         .|.|:.|
plant    84 RKDLSSVLIRATFVYRNYDSQNSPPAFHVSLGRRITSTVDLRTNDPWIEELVWPVNNDSLLL--- 145

  Fly   258 VSIECLLE--------DSALE--PKITWLHKGNADNIDDLLQR-------------LR------- 292
                |||.        .|:||  |.....:|.:.:...|::.|             :|
plant   146 ----CLLAVKGRGIPVISSLEVRPLPLGSYKYSLEGSPDIILRRSYRINSGYTNGTIRYPSDPFD 206

  Fly   293 -----EQSQLPV-------DVTRL----ITRMDEPQVLRLGNVLMEDGGWYICIAENQVGRTVAA 341
                 :||..|.       .:|:|    ||......||:...:|               .|..:.
plant   207 RIWDPDQSYSPFHASWSFNGLTKLNSFNITENPPASVLKTARIL---------------ARKESL 256

  Fly   342 SY-VDLYSPSDTTTVRTTTTTTVASPIPTASTGEDNDDDVENPAAEASGGVGPPVFRKELKRLQH 405
            || :.|::|.|...:.........||..:.:.   ||:..::.....|...|...|      .|.
plant   257 SYTLSLHTPGDYYIILYFAGILSLSPSFSVTI---NDEVKQSDYTVTSSEAGTLYF------TQK 312

  Fly   406 SLSGNTVNLACPVYGKANITWTKDK-KPLNRELGVY------VQKNWT----LRFVEA-TSEDSG 458
            .:|            |.|||..|.| .|....|.||      .:.:.|    |:.:|. |.:|.|
plant   313 GIS------------KLNITLRKIKFNPQVSALEVYEILQIPPEASSTTVSALKVIEQFTGQDLG 365

  Fly   459 LYNCKVCNAWGCIQFDFSVQINDRTRSAPIIVVPQNQTVKVNG----SLVMKCTVYSDLHPT--- 516
                     |               :..|...:|.|. ::..|    ||.:.......:.||
plant   366 ---------W---------------QDDPCTPLPWNH-IECEGNRVTSLFLSKINLRSISPTFGD 405

  Fly   517 -VSWKRVVLKNASLDG-------LKSVEIQNLNF-------TVTNDSV---VLTLRNVTF----- 558
             :..|.:.|.|.||.|       ||.::..||:|       :...|.|   ||.|:|.:.
plant   406 LLDLKTLDLHNTSLTGAIQNVGSLKDLQKLNLSFNQLESFGSELEDLVNLEVLDLQNNSLQGSVP 470

  Fly   559 DQEGWYTCLASSGLGRSNSSVYLRVVSPLPP------LEI---------YALLHAHPLGFTL--A 606
            :..|....|....|..:|      :|.|||.      ||:         ::.:..:.:..|:  .
plant   471 ETLGKLKKLRLLNLENNN------LVGPLPQSLNITGLEVRITGNPCLSFSSISCNNVSSTIDTP 529

  Fly   607 AITI-----------VALFL---LGSAFITFMLRRLRREKLLKLRIETVHQWTKKVIIYRPGGEE 657
            .:||           :|:.|   .|:.|.||::       .:.:.|.|..|..|:..|.|
plant   530 QVTIPINKKQRKQNRIAILLGVSGGALFATFLV-------FVFMSIFTRRQRNKERDITR----- 582

  Fly   658 GSGCSSGDLQMPVIRIEKQRTTVSTTGTGGTDPAQGFNEYEFPLDSNWEIPRQQLSLGSILGEGA 722
                  ..|:|                       |.:|...  :.|:.||.....:...::|.|:
plant   583 ------AQLKM-----------------------QNWNASR--IFSHKEIKSATRNFKEVIGRGS 616

  Fly   723 FGRVVMAEAEGLPRSPQLAETIVAVKMVKEEHTDTDMASLVREMEVMKMIGKHINIINLLGCCSQ 787
            ||.|...:   ||...|     |||| |:.:.|.....|.:.|:.::..| :|.|:::..|.|.:
plant   617 FGAVYRGK---LPDGKQ-----VAVK-VRFDRTQLGADSFINEVHLLSQI-RHQNLVSFEGFCYE 671

  Fly   788 GGPLWVIVEYAPHGNLKDFLKQNRPGAPQRRSDSDGYLDDKPLISTQH-LGEKELTKFAFQIARG 851
            .....::.||...|:|.|.|...|                    |.:| |......|.|...|:|
plant   672 PKRQILVYEYLSGGSLADHLYGPR--------------------SKRHSLNWVSRLKVAVDAAKG 716

  Fly   852 MEYL---ASRRCIHRDLAARNVLVSDGYVMKIADFGLAR-----DIQDTEYYRKNTNGRLPIKWM 908
            ::||   :..|.||||:.:.|:|:......|::||||::     |........|.|.|.|..::.
plant   717 LDYLHNGSEPRIIHRDVKSSNILLDKDMNAKVSDFGLSKQFTKADASHITTVVKGTAGYLDPEYY 781

  Fly   909 APESLQEKKYDSQSDVWSYGVLLWEIMTYGDQPYPHILSAEELYSYLITGQRME----------- 962
            :...|.||     |||:|:||:|.|::. |.:|..|..|.:.....|.....::
plant   782 STLQLTEK-----SDVYSFGVVLLELIC-GREPLSHSGSPDSFNLVLWARPNLQAGAFEIVDDIL 840

  Fly   963 ----KPAKCSLNIYVVMRQCWHFESCARPTFAELVESFDGILQQASS 1005
                .||.......:.:| |...::..||:.||::..    |::|.|
plant   841 KETFDPASMKKAASIAIR-CVGRDASGRPSIAEVLTK----LKEAYS 882

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
btl	NP_001014583.1	IG_like	149..232	CDD:214653	21/93 (23%)
		IGc2	157..215	CDD:197706	15/60 (25%)
		IG	247..336	CDD:214652	25/143 (17%)
		Ig	258..340	CDD:143165	22/127 (17%)
		I-set	394..479	CDD:254352	20/96 (21%)
		IGc2	408..469	CDD:197706	17/72 (24%)
		IG_like	492..583	CDD:214653	28/120 (23%)
		Ig	507..583	CDD:299845	23/101 (23%)
		PKc_like	700..1000	CDD:304357	81/323 (25%)
		TyrKc	712..996	CDD:197581	78/307 (25%)
AT5G48740	NP_199685.2	Malectin_like	24..338	CDD:403886	73/357 (20%)
AT5G48740	NP_199685.2	STKc_IRAK	612..879	CDD:270968	79/307 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	98	1.000	Inparanoid score	I2197
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050