DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment btl and CRK23

DIOPT Version :9

Sequence 1:	NP_001014583.1	Gene:	btl / 39564	FlyBaseID:	FBgn0285896	Length:	1052	Species:	Drosophila melanogaster
Sequence 2:	NP_194062.1	Gene:	CRK23 / 828430	AraportID:	AT4G23310	Length:	830	Species:	Arabidopsis thaliana

Alignment Length:	802	Identity:	178/802 - (22%)
Similarity:	291/802 - (36%)	Gaps:	240/802 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   228 TQLEVISRKHTVPMLKPGYPRNTSI-ALGDNVS--IECLLEDSALEPKITWLHKGNADNIDDLLQ 289
            |.|..:|..........|: ||.:: ...|.|:  .:|   ...|.|::  .|...|..:.|.|.
plant    51 TLLSFLSSPDASSSYSSGF-RNDAVGTFPDRVTGLFDC---RGDLPPEV--CHNCVAFAVKDTLI 109

  Fly   290 RLREQSQLPVDVTRLITRMDEPQVLRLGNVLMEDGGWYICIAENQVGRTVAASYVDLYSPSDTTT 354
            |...:        |.:|...:...||..|::              |...:..:||....||..|.
plant   110 RCPNE--------RDVTLFYDECTLRYSNLV--------------VTSALDPTYVYHVCPSWATF 152

  Fly   355 VRTTT--------TTTVASPIPTASTGEDNDDDVENP-----AAEASGGVGPPVFRKELKRLQHS 406
            .|::|        .:|::||..:.|||..|....::|     .....|.|.|.|.|:.:     |
plant   153 PRSSTYMTNLITLLSTLSSPSASYSTGFQNATAGKHPDRVTGLFNCRGDVSPEVCRRCV-----S 212

  Fly   407 LSGNTVNLACPV--------------YGKANITWTKDKKPLNRELGVYV--QKNWT----LRFVE 451
            .:.|..:..||:              |...||..|.     |...|:.:  .:|.|    .||.:
plant   213 FAVNETSTRCPIEKEVTLYYDQCTLRYSNRNILSTS-----NTNGGIILANSQNMTSNEQARFKD 272

  Fly   452 -----------ATSEDSGLYNCKVCNAWGCIQFDFSVQ-INDRTRSAPIIVVPQ--NQ--TVKVN 500
                       |.:..|..::.:..|..........|| .:|.||...:..:.|  ||  |.|:.
plant   273 LVLTTMNQATIAAANSSKRFDARSANFTTLHSLYTLVQCTHDLTRQDCLSCLQQIINQLPTEKIG 337

  Fly   501 GSLVMK--------CTVYSDLHPTVSWKRVVLKNAS-----------LDGLKSVEIQNLNFTVTN 546
            |..::.        |..|:....|....:   :|::           ..||.|           .
plant   338 GQFIVPSCSSRFELCLFYNQSAVTTPQPQ---QNSAPPPPPTSIPSPRPGLNS-----------R 388

  Fly   547 DSVVLTLRNVTFDQ-----EGWYTCL------ASSGLGRSNSSVYLRVVSPLPPLEIYALLHAHP 600
            ..::..|..|:|::     :..:.|:      .::|.|.::|.:.:.||
plant   389 FPLITCLSAVSFEKFKDLLKPGFICILIKIVSENTGKGGNSSVIIIAVV---------------- 437

  Fly   601 LGFTLAAITIVALFLLGSAFITFMLRRLRREKLLKLRIETVHQWTKKVIIYRPGGEEG-SGCSSG 664
                   ::|.||.||..|  .|.:|..||:|::. .|..::...|...:..|..|.| |..::|
plant   438 -------VSITALLLLFVA--VFSVRTKRRKKMIG-AIPLLNVKRKDTEVTEPLAENGDSITTAG 492

  Fly   665 DLQMPVIRIEKQRTTVSTTGTGGTDPAQGFNEYEFPLDSNWEIPRQQLSLGSILGEGAFGRVVMA 729
            .||...      :..|:.|           |.: .|::.              ||:|.||.|...
plant   493 SLQFDF------KAIVAAT-----------NNF-LPINK--------------LGQGGFGEVYKG 525

  Fly   730 EAEGLPRSPQLAETIVAVKMVKEEHTDTDMASLVREME-----VMKMIGKHINIINLLGCCSQGG 789
            .   .|...|     ||||.:.:.....:     ||.|     |.|:  :|.|::.|||.|.:|.
plant   526 T---FPSGVQ-----VAVKRLSKTSGQGE-----REFENEVVVVAKL--QHRNLVRLLGYCLEGE 575

  Fly   790 PLWVIVEYAPHGNLKDFLKQNRPGAPQRRSDSDGYLDDKPLISTQHLGEKELTKFAFQIARGMEY 854
            ...::.|:..:.:|                  |.:|.|..:  .:.|......|....||||:.|
plant   576 EKILVYEFVHNKSL------------------DYFLFDTTM--KRQLDWTRRYKIIGGIARGILY 620

  Fly   855 L---ASRRCIHRDLAARNVLVSDGYVMKIADFGLAR--DIQDTEYYRKNTNGRLPIKWMAPESLQ 914
            |   :....|||||.|.|:|:......|:||||:||  .:..||...:...|  ...:||||...
plant   621 LHQDSRLTIIHRDLKAGNILLDADMNPKVADFGMARIFGMDQTEANTRRVVG--TYGYMAPEYAM 683

  Fly   915 EKKYDSQSDVWSYGVLLWEIMT 936
            ..::..:|||:|:|||::||::
plant   684 YGQFSMKSDVYSFGVLVFEIIS 705

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
btl	NP_001014583.1	IG_like	149..232	CDD:214653	2/3 (67%)
		IGc2	157..215	CDD:197706
		IG	247..336	CDD:214652	17/91 (19%)
		Ig	258..340	CDD:143165	15/83 (18%)
		I-set	394..479	CDD:254352	21/116 (18%)
		IGc2	408..469	CDD:197706	16/91 (18%)
		IG_like	492..583	CDD:214653	20/124 (16%)
		Ig	507..583	CDD:299845	14/97 (14%)
		PKc_like	700..1000	CDD:304357	69/247 (28%)
		TyrKc	712..996	CDD:197581	68/235 (29%)
CRK23	NP_194062.1	Stress-antifung	33..129	CDD:279926	20/91 (22%)
		Stress-antifung	145..240	CDD:279926	22/99 (22%)
		Stress-antifung	258..350	CDD:279926	18/91 (20%)
		TyrKc	511..780	CDD:197581	68/246 (28%)
		STKc_IRAK	514..781	CDD:270968	68/229 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000