DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment btl and CRK12

DIOPT Version :9

Sequence 1:	NP_001014583.1	Gene:	btl / 39564	FlyBaseID:	FBgn0285896	Length:	1052	Species:	Drosophila melanogaster
Sequence 2:	NP_001320040.1	Gene:	CRK12 / 828419	AraportID:	AT4G23200	Length:	659	Species:	Arabidopsis thaliana

Alignment Length:	511	Identity:	116/511 - (22%)
Similarity:	188/511 - (36%)	Gaps:	175/511 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   485 SAPIIVVPQNQTVKVNGSLVMKCTVYSDLHPTVSWKRVVLKNASLDGLKSVEIQNLNFTVTNDSV 549
            :|.:..:|.:||:..    :|:||  .||.|.                      ..|..:| :||
plant   179 TADVAALPDSQTLYA----MMQCT--PDLSPA----------------------ECNLCLT-ESV 214

  Fly   550 VLTLRNVTFDQEGWYTCLASSGLGRSNSSVYLRVVSPLPPLEIY------ALLHAHPLG------ 602
            |           .:.:|.    |||...|:..  :|.....|:|      .::.|.||.
plant   215 V-----------NYQSCC----LGRQGGSIVR--LSCAFRAELYPFGGAFTVMTARPLSQPPPSL 262

  Fly   603 ----------FTLAAIT----IVALFLLGSAFITFMLRRL--RREKLLKLRIETVHQWTKKVIIY 651
                      .|:|||.    :||:..|    :..:|.||  ||.|..:
plant   263 IKKDSGKFSTETIAAIVVPIIVVAIIFL----VLLVLSRLFARRRKSYQ---------------- 307

  Fly   652 RPGGEEGSGCSSGDLQMPVIRIEKQRTTVSTTGTGGTDPAQGFNEYEFPLDSNWEIPRQQLSLGS 716
                                .|:..::.::|.         .|.:.:|   ...|:..:..:..:
plant   308 --------------------EIDLDQSGITTL---------HFQQLDF---KTIEVATENFAKTN 340

  Fly   717 ILGEGAFGRVVMAEAEGLPRSPQLAETIVAVKMVKEEHTDTDMASLVREMEVMKMIGKHINIINL 781
            .||:|.||.|.        :...:..|.||||.:.:  |....|...:...|:....:|.|::.|
plant   341 KLGQGGFGEVY--------KGTLVNGTEVAVKRLSK--TSEQGAQEFKNEVVLVAKLQHRNLVKL 395

  Fly   782 LGCCSQGGPLWVIVEYAPHGNLKDFL----KQNRPGAPQRRSDSDGYLDDKPLISTQHLGEKELT 842
            ||.|.:.....::.|:.|:.:|..||    ||.:....:|.:...|
plant   396 LGYCLEPEEKILVYEFVPNKSLDYFLFDPTKQGQLDWTKRYNIIGG------------------- 441

  Fly   843 KFAFQIARGMEYL---ASRRCIHRDLAARNVLVSDGYVMKIADFGLARDIQDTEYYRKNTNGRL- 903
                 |.||:.||   :....|||||.|.|:|:....:.||||||:|| |...:....||. |:
plant   442 -----ITRGILYLHQDSRLTIIHRDLKASNILLDADMIPKIADFGMAR-ISGIDQSVANTK-RIA 499

  Fly   904 -PIKWMAPESLQEKKYDSQSDVWSYGVLLWEIMTYGDQP---YPHILSAEELYSYL 955
             ...:|.||.:...::..:|||:|:|||:.||:. |.:.   |.....||.|.:|:
plant   500 GTFGYMPPEYVIHGQFSMKSDVYSFGVLILEIIC-GKKNRSFYQADTKAENLVTYV 554

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
btl	NP_001014583.1	IG_like	149..232	CDD:214653
		IGc2	157..215	CDD:197706
		IG	247..336	CDD:214652
		Ig	258..340	CDD:143165
		I-set	394..479	CDD:254352
		IGc2	408..469	CDD:197706
		IG_like	492..583	CDD:214653	19/90 (21%)
		Ig	507..583	CDD:299845	15/75 (20%)
		PKc_like	700..1000	CDD:304357	73/268 (27%)
		TyrKc	712..996	CDD:197581	72/256 (28%)
CRK12	NP_001320040.1	Stress-antifung	24..120	CDD:307677
		Stress-antifung	<166..237	CDD:307677	21/103 (20%)
		STKc_IRAK	342..610	CDD:270968	72/250 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000