DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment btl and AT2G23200

DIOPT Version :9

Sequence 1:	NP_001014583.1	Gene:	btl / 39564	FlyBaseID:	FBgn0285896	Length:	1052	Species:	Drosophila melanogaster
Sequence 2:	NP_179901.1	Gene:	AT2G23200 / 816852	AraportID:	AT2G23200	Length:	834	Species:	Arabidopsis thaliana

Alignment Length:	791	Identity:	161/791 - (20%)
Similarity:	277/791 - (35%)	Gaps:	251/791 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   324 GGWYICIAENQVGRTVAASYVD-LYSPSDTTTVRTTTTTTVASPIPTASTGEDNDDDVENPAAEA 387
            ||..|....:.:|||......| ||.......:.:|.|......:                 :.|
plant   213 GGEKITPDNDTLGRTWLPDDDDFLYRKDSARNINSTQTPNYVGGL-----------------SSA 260

  Fly   388 SGGVGPPVFRKELKRLQHSLSGNTVNLACPVYGKANITWTKDKKPLNRELGVYVQKNWTLRFVEA 452
            :....|....|..|.:..| |...|.:.      .|:||:...|..:|.   :::.:::......
plant   261 TDSTAPDFVYKTAKAMNRS-SNEQVGML------MNVTWSFKVKSNHRH---FIRIHFSDILSNL 315

  Fly   453 TSEDSGLYNCKVCNAWGCIQFDFSVQINDRTRSAPIIVVPQNQTVKVNGSLVMKCTVYSD----L 513
            ::.||                ||.:.:|...|   :.|.|..|. ::...........||    |
plant   316 SNSDS----------------DFYLFVNGYWR---VDVKPSEQP-RLASPFFKDVVNVSDGSGLL 360

  Fly   514 HPTVSWKRVVLKNASLDGLKSVEIQNLNFTVTNDSVVLTLRNVTFDQEGWYTCLASSGLGRSN-S 577
            :.::..|........|:||:.:|:                             |:.||...|| |
plant   361 NISIGTKEANKDAGFLNGLEMMEV-----------------------------LSKSGSDYSNRS 396

  Fly   578 SVYLRVVSPLPPLEIYALLHAHPLGFTLAAITIVALFLLGSAFITFMLRRLRREKLLKLRIE-TV 641
            |..:.:::                |..:||....|| :....|:.|:.|  ||.|..|..:| ||
plant   397 SSRVHIIT----------------GCAVAAAAASAL-VFSLLFMVFLKR--RRSKKTKPEVEGTV 442

  Fly   642 HQWTKKVIIYRPGGEEGSGCSSGDLQMPVIRIEKQRTTVSTTGTGGTDPAQGFNEYEFPLDSNWE 706
              |:                     .:|:.|             ||:...:..::|.       .
plant   443 --WS---------------------PLPLHR-------------GGSSDNRPISQYH-------N 464

  Fly   707 IPRQQLSLG------------------SILGEGAFGRVVMAEAEGLPRSPQLAETIVAVKMVKEE 753
            .|.:.|.||                  .::|:|.||.|..|.   ||...:.|        :|..
plant   465 SPLRNLHLGLTIPFTDILSATNNFDEQLLIGKGGFGYVYKAI---LPDGTKAA--------IKRG 518

  Fly   754 HTDTDMASL--VREMEVMKMIGKHINIINLLGCCSQGGPLWVIVEYAPHGNLKDFLKQNRPGAPQ 816
            .|.:....|  ..|::|:..| :|.::::|.|.|.:...:.::.|:...|.||:.|
plant   519 KTGSGQGILEFQTEIQVLSRI-RHRHLVSLTGYCEENSEMILVYEFMEKGTLKEHL--------- 573

  Fly   817 RRSDSDGYLDDKPLISTQHLGEKELTKFAFQIARGMEYLASR----RCIHRDLAARNVLVSDGYV 877
                   |..:.|.::.     |:..:.....|||::||.|.    ..||||:.:.|:|:.:..:
plant   574 -------YGSNLPSLTW-----KQRLEICIGAARGLDYLHSSGSEGAIIHRDVKSTNILLDEHNI 626

  Fly   878 MKIADFGLAR-DIQDTEYYRKNTNGRLPIKWMAPESLQEKKYDSQSDVWSYGVLLWEIM--TYGD 939
            .|:|||||:: ..||......|..|  ...::.||.||..|...:|||:::||:|.|::  ....
plant   627 AKVADFGLSKIHNQDESNISINIKG--TFGYLDPEYLQTHKLTEKSDVYAFGVVLLEVLFARPAI 689

  Fly   940 QPY-PH--------IL------SAEELYSYLITGQRMEKPAKCSLNIYVVMRQCWHFESCARPTF 989
            .|| ||        ::      :.:|:....:.||......|..:.|   ..:|.......||:.
plant   690 DPYLPHEEVNLSEWVMFCKSKGTIDEILDPSLIGQIETNSLKKFMEI---AEKCLKEYGDERPSM 751

  Fly   990 AELVESFDGILQ-QASSNPNDAYLD----------LSMPMLETPPS--------SGDED------ 1029
            .:::...:.:|| |..:|..:|:.:          |..|.|....|        :|||.
plant   752 RDVIWDLEYVLQLQMMTNRREAHEEDSTAINSGGSLVAPRLMVSDSFSTNSIFQNGDESKNRFGF 816

  Fly  1030 -DGSDTETFRE 1039
             |.|:|..|.:
plant   817 TDSSETRVFSQ 827

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
btl	NP_001014583.1	IG_like	149..232	CDD:214653
		IGc2	157..215	CDD:197706
		IG	247..336	CDD:214652	3/11 (27%)
		Ig	258..340	CDD:143165	6/15 (40%)
		I-set	394..479	CDD:254352	14/84 (17%)
		IGc2	408..469	CDD:197706	9/60 (15%)
		IG_like	492..583	CDD:214653	17/95 (18%)
		Ig	507..583	CDD:299845	15/80 (19%)
		PKc_like	700..1000	CDD:304357	77/341 (23%)
		TyrKc	712..996	CDD:197581	76/325 (23%)
AT2G23200	NP_179901.1	Malectin_like	41..383	CDD:289580	39/216 (18%)
		STKc_IRAK	494..759	CDD:270968	73/302 (24%)
		TyrKc	494..758	CDD:197581	73/301 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	98	1.000	Inparanoid score	I2197
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050