Protein Alignment btl and ptk6a

DIOPT Version :10

• Sequence 1: NP_729956.1
• Gene: btl / 39564
• FlyBaseID: FBgn0285896
• Length: 1052
• Species: Drosophila melanogaster
• Sequence 2: XP_682778.7
• Gene: ptk6a / 555232
• ZFINID: ZDB-GENE-081105-117
• Length: 510
• Species: Danio rerio
• Alignment Length: 552
• Identity: 149/552 - (26%)
• Similarity: 237/552 - (42%)
• Gaps: 126/552 - (22%)

  Fly   481 DRTRSAPIIVVPQN---QTVKV-NGSLVMKCTVYSDLHPTVSWKRVVLKNASLDGLKSVEIQNLN 541
            |:|.:..    |.|   |||.| |.|....|...|:|:..: |.   .|....|.|...|.:...
Zfish    25 DKTEAEK----PTNTAKQTVNVPNPSRASACEPGSELYKAL-WS---YKARGADELSFQEGEQFR 81

  Fly   542 F-----------------TVTNDSVV---LTLRNVTFDQEGWYTCLASSGLGRSNSSVYLRVVSP 586
            .                 .||....|   ...|..|..::.||    ...|.|..:.:.|..
Zfish    82 ICERQGEWWTALKLGRDGAVTGRGFVPNHFLARRQTVKEQPWY----FGTLNRFETEILLLA--- 139

  Fly   587 LPPLEIYALLHAHP----LGFTLAAITIVALFLLGSAFITFMLRRLRREKLLKL----------- 636
             |..::.|.|..|.    :|:.|:.::       |.        |.|..|.:|:
Zfish   140 -PENDVGAFLVRHSEKDNIGYVLSVLS-------GD--------RSREVKHIKIHQNQNESFYLD 188

  Fly   637 RIETVHQWTKKVIIYRPGGEEGSGCSSGDLQMPVIRIEKQRTTVSTTGTGGTDPAQGFNEYEFPL 701
            :.:|.....|.|..|.....:|...    |:.|..|.|.:...:|.:..
Zfish   189 KSQTFQSLEKLVDYYWKYSLDGDSF----LKQPCRRPEPKPKDLSHSTV---------------- 233

  Fly   702 DSNWEIPRQQLSLGSILGEGAFGRVVMAEAEGLPRSPQLAETIVAVKMVKEEHTDTDMASLVREM 766
             ::||:|:::.:|...||:|.|..|...:.:|:..        ||:|::|.:  ..:....:.|.
Zfish   234 -NDWELPKEEFTLEEELGKGFFADVYRGKWKGMVN--------VAIKILKND--SINHREFMLET 287

  Fly   767 EVMKMIGKHINIINLLGCCSQGGPLWVIVEYAPHGNLKDFLKQNRPGAPQRRSDSDGYLDDKPLI 831
            :::|.: :|.::|.|...|:...|.::|.|....|:|...||           ..:|
Zfish   288 QILKKL-RHKHLIALFAVCTSSSPFYIITELMEKGDLLSLLK-----------GKEG-------- 332

  Fly   832 STQHLGEKELTKFAFQIARGMEYLASRRCIHRDLAARNVLVSDGYVMKIADFGLARDIQDTEYYR 896
              |.|..:.||:.|.|:|.||.||..:..||||||||||||...|:.|:||.||||.::::.|
Zfish   333 --QDLNAQMLTEMASQVADGMAYLEEQNSIHRDLAARNVLVGANYICKVADLGLARIVKESVY-- 393

  Fly   897 KNTNGRLPIKWMAPESLQEKKYDSQSDVWSYGVLLWEIMTYGDQPYPHILSAEELYSYLITGQRM 961
            .:.:.::|.||.|||::...::.::|||||:||||:|:.|||..||| ..|..|:|:.:.:|.||
Zfish   394 SSEDAQIPYKWSAPEAISHGRFSNKSDVWSFGVLLYEMFTYGGVPYP-AFSNIEVYNMITSGYRM 457

  Fly   962 EKPAKCSLNIYVVMRQCWHFESCARPTFAELV 993
            ..|..|..:||.:|..||.:.:..||.|:||:
Zfish   458 PAPPNCPSHIYDIMLMCWRYSAEERPDFSELL 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
btl	NP_729956.1	Ig	143..215	CDD:472250
		Ig strand B	160..164	CDD:409570
		Ig strand C	175..179	CDD:409570
		Ig strand E	197..201	CDD:409570
		Ig strand F	211..215	CDD:409570
		Ig_3	247..333	CDD:464046
		Ig	398..479	CDD:472250
		Ig strand B	412..416	CDD:409393
		Ig strand C	423..427	CDD:409393
		Ig strand E	445..449	CDD:409393
		Ig strand F	459..464	CDD:409393
		Ig strand G	472..475	CDD:409393
		IG_like	492..583	CDD:214653	26/114 (23%)
		Ig strand B	503..507	CDD:409444	0/3 (0%)
		Ig strand C	516..520	CDD:409444	0/3 (0%)
		Ig strand E	549..553	CDD:409444	1/6 (17%)
		Ig strand F	563..568	CDD:409444	2/4 (50%)
		Ig strand G	576..579	CDD:409444	0/2 (0%)
		Protein Kinases, catalytic domain	700..1000	CDD:473864	100/294 (34%)
ptk6a	XP_682778.7	SH3_Brk	57..114	CDD:212781	9/60 (15%)
		SH2	121..208	CDD:214585	20/109 (18%)
		Protein Kinases, catalytic domain	236..488	CDD:473864	98/286 (34%)