DRSC/TRiP Functional Genomics Resources

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Protein Alignment btl and fgfrl1a

DIOPT Version :9

Sequence 1:NP_001014583.1 Gene:btl / 39564 FlyBaseID:FBgn0285896 Length:1052 Species:Drosophila melanogaster
Sequence 2:NP_956670.1 Gene:fgfrl1a / 393347 ZFINID:ZDB-GENE-040128-2 Length:483 Species:Danio rerio


Alignment Length:443 Identity:113/443 - (25%)
Similarity:167/443 - (37%) Gaps:101/443 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly   221 DCQRSNPTQLEVISRKHTVPMLKPGYPRNTSIALGDNVSIECLLEDSALEPKITWLHKGNADNID 285
            ||.|..|...|.|:.:.||             .:|..:.::|.:|... .|.|.|...|.  ||.
Zfish    18 DCARGPPRVAEKIAHRQTV-------------RIGRTMKLQCPVEGDP-PPLIMWTKDGR--NIH 66

  Fly   286 DLLQRLREQSQLPVDVTRLITRMDEPQVLRLGNVLMEDGGWYICIAENQVGRTVAASYVDLYSPS 350
            ....|.|...                |.||:..|..:|.|.:||.|.|..|              
Zfish    67 SGWMRFRVLQ----------------QALRIKEVEADDAGTFICKATNGFG-------------- 101

  Fly   351 DTTTVRTTTTTTVASPIPTASTGEDNDDDVENPAAEA------SGGVGPPVFRKELKRLQHSLS- 408
               :|....|..|   |..:|.|.:.    ..||.|.      :|.:..|.|.:..|..:..:: 
Zfish   102 ---SVNINYTLIV---IDDSSAGREG----ARPAGETEYSTDLTGKLVRPRFTQPAKMRKRVIAR 156

  Fly   409 --GNTVNLACPVYG--KANITWTKDKKPLN-RELGVYVQKNWTLRFVEATSEDSGLYNCKVCNAW 468
              |::|.|.|...|  :.:|.|.||.:||. .|:|...:|.|||.....|.|.||.|.|.|.|..
Zfish   157 PVGSSVRLKCTASGNPRPDIVWLKDSRPLTPEEVGEGRKKKWTLSLKNLTPEHSGKYTCHVSNRA 221

  Fly   469 GCIQFDFSVQINDRTRSAPII--VVPQNQTVKVNGSLVMKCTVYSDLHPTVSWKRVVLKNASLDG 531
            |.|...:.|::..||.|.||:  ..|.|.||...|:...:|.|.||:.|.:.|.:.|........
Zfish   222 GEINATYKVEVIQRTNSKPILTGTHPVNTTVDYGGTTSFQCKVRSDVKPVIQWLKRVEPGGEGKY 286

  Fly   532 LKSVEIQNLNFTVTNDSVV-----------LTLRNVTFDQEGWYTCLASSGLGRSNSSVYLRVV- 584
            ..::|:.:.:|.|.....|           |.:.....:..|.|.||.::.:|.|..|.:|.|: 
Zfish   287 NSTIEVGDHHFVVLPTGDVWSRPDGSYLNKLLITRAKEEDAGMYICLGANTMGYSFRSAFLTVLP 351

  Fly   585 ----------SPLPPLEIYALLHAHPLGFTLAAITIVALFLLGSAFITFMLRR 627
                      |.|||...:.::...|.|.         :|:||:..:.|...|
Zfish   352 DPKPPFSPIPSVLPPSLPWPVIIGIPAGI---------VFILGTVLLWFCQSR 395

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
btlNP_001014583.1 IG_like 149..232 CDD:214653 4/10 (40%)
IGc2 157..215 CDD:197706
IG 247..336 CDD:214652 21/88 (24%)
Ig 258..340 CDD:143165 21/81 (26%)
I-set 394..479 CDD:254352 31/90 (34%)
IGc2 408..469 CDD:197706 25/66 (38%)
IG_like 492..583 CDD:214653 25/101 (25%)
Ig 507..583 CDD:299845 20/86 (23%)
PKc_like 700..1000 CDD:304357
TyrKc 712..996 CDD:197581
fgfrl1aNP_956670.1 I-set 32..111 CDD:254352 26/127 (20%)
IGc2 38..101 CDD:197706 21/81 (26%)
I-set 141..232 CDD:254352 31/90 (34%)
Ig2_FGFRL1-like 151..232 CDD:143264 28/80 (35%)
I-set 245..349 CDD:254352 25/103 (24%)
Ig 255..350 CDD:299845 21/94 (22%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0200
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.810

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