DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment btl and CG10702

DIOPT Version :9

Sequence 1:	NP_001014583.1	Gene:	btl / 39564	FlyBaseID:	FBgn0285896	Length:	1052	Species:	Drosophila melanogaster
Sequence 2:	NP_001188841.1	Gene:	CG10702 / 35181	FlyBaseID:	FBgn0032752	Length:	946	Species:	Drosophila melanogaster

Alignment Length:	307	Identity:	56/307 - (18%)
Similarity:	101/307 - (32%)	Gaps:	121/307 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 VTVENSPRQRHLLSDMDITLQCVRPMAKWFYEDKFQLRATLLRLERAQSGNSGNYGCLDSQNRWY 98
            :|:.|...:..|.... .:::.||...|.:...:.:....|..|||.
  Fly   338 ITIRNKVNETQLYQSF-TSMREVRGHVKVYRSSQLRSLQFLRNLERV------------------ 383

  Fly    99 NISLVVGHKEPVGNDIASFVKLEDAPALPESDLFFQPLNESRSLKLLQPLPKTVQRTAGGLFQLN 163
                   |.:|:.|...||: |.|...|.|   .:.|   ||.|:.::          ||:|
  Fly   384 -------HGDPLENRHYSFI-LYDNKELSE---LWTP---SRQLEFME----------GGMF--- 421

  Fly   164 CSPMDPDAKGVNISWLHNDTQILGGRGR-----IKLKRWSLTVGQLQPEDAGSYHCELCVEQDCQ 223
                           :|.:.::...|.|     :...|   .:..||..|.         |..|
  Fly   422 ---------------MHRNNKLCNRRMREFQNAVTHDR---ALDSLQTNDQ---------EVQC- 458

  Fly   224 RSNPTQLEVISRKHTVPMLKPGYPRNTSIALGDNVSIECLLEDSALEPKITWLHKGNADNIDDLL 288
              :|.:|::..:|.|          :.|:                   |::||....:..| :|:
  Fly   459 --SPLKLQLYVQKRT----------HRSV-------------------KLSWLKSQTSQKI-ELI 491

  Fly   289 QR-------LREQSQLPVDVTRLITRMDEPQVLRLGNVLMEDGGWYI 328
            .|       ..|:|:|...:   .||::..:.|...:.|:|:|..|:
  Fly   492 HRPLLPGKLYHEESELDAPI---CTRINWKRRLLFPDDLIENGTHYL 535

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
btl	NP_001014583.1	IG_like	149..232	CDD:214653	14/87 (16%)
		IGc2	157..215	CDD:197706	10/62 (16%)
		IG	247..336	CDD:214652	17/89 (19%)
		Ig	258..340	CDD:143165	16/78 (21%)
		I-set	394..479	CDD:254352
		IGc2	408..469	CDD:197706
		IG_like	492..583	CDD:214653
		Ig	507..583	CDD:299845
		PKc_like	700..1000	CDD:304357
		TyrKc	712..996	CDD:197581
CG10702	NP_001188841.1	Recep_L_domain	47..159	CDD:279382
		Furin-like	171..297	CDD:279142
		FU	210..258	CDD:238021
		Recep_L_domain	328..441	CDD:279382	29/163 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24416
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100