DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment btl and Pdgfrl

DIOPT Version :9

Sequence 1:	NP_001014583.1	Gene:	btl / 39564	FlyBaseID:	FBgn0285896	Length:	1052	Species:	Drosophila melanogaster
Sequence 2:	NP_001011921.1	Gene:	Pdgfrl / 290771	RGDID:	1308028	Length:	375	Species:	Rattus norvegicus

Alignment Length:	349	Identity:	76/349 - (21%)
Similarity:	129/349 - (36%)	Gaps:	109/349 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 LLSDMDITLQCVRPMAKWFYE---DKFQ-LRATLLRLER--------AQSGNSGNYGCLDSQNRW 97
            |::...:.|:|.....:|.|.   |.|: .|.|:.:.||        :.:.::|.:.|      |
  Rat    86 LMAGQSVELRCKGSKVEWSYPAYLDTFKDSRLTVKQNERYGQLTLVNSTTADTGEFSC------W 144

  Fly    98 YNISLVVGHKEPVGNDIASFVKLEDAPALPESDLFFQPLNESRSLKLLQPLPKTVQRTAGGLFQL 162
                      |.:.|   .::...|......:.:||....|     |..|.|....     :..|
  Rat   145 ----------ERLCN---GYICRRDEARTGSTYIFFTEKGE-----LFVPSPSYFD-----VVYL 186

  Fly   163 N--------CSPMDPDAKGVNISWLH----------NDTQILGGRGRIKLKRWSLTVGQLQP--E 207
            |        |....|.||..    ||          |.|.|:     ..:||..:   .|||  :
  Rat   187 NPDRQAVVPCRVTAPSAKVT----LHREFPAKEIPANGTDIV-----YDMKRGFV---YLQPHSD 239

  Fly   208 DAGSYHCELCVEQDCQRSNPTQLEVISRKHTVPMLK-PGYPRNTSIAL-------GDNVSIEC-L 263
            ..|..:|:      .:....:|:.|   |:.:..:: |..|.:|:|..       ||::|:.| :
  Rat   240 HQGVVYCK------AEAGGKSQISV---KYQLLYVEVPSGPPSTTILASSNKVRGGDDISVLCTV 295

  Fly   264 LEDSALEPKITWLHKGNADNIDDLLQRLREQSQLPVDVTRLI-------TRMDEPQVLRLGNVLM 321
            |.:..:|.:..|:..|..|.....:|          |..|||       ||:.: .|:.:.:...
  Rat   296 LGEPDVEVEFRWIFPGQKDERPVTIQ----------DTWRLIHRGLGHTTRISQ-SVITVEDFET 349

  Fly   322 EDGGWYICIAENQVGRTVAASYVD 345
            .|.|:|||.|:|..|:|..|:.|:
  Rat   350 IDAGYYICTAQNLRGQTTVATTVE 373

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
btl	NP_001014583.1	IG_like	149..232	CDD:214653	20/102 (20%)
		IGc2	157..215	CDD:197706	17/77 (22%)
		IG	247..336	CDD:214652	27/103 (26%)
		Ig	258..340	CDD:143165	24/89 (27%)
		I-set	394..479	CDD:254352
		IGc2	408..469	CDD:197706
		IG_like	492..583	CDD:214653
		Ig	507..583	CDD:299845
		PKc_like	700..1000	CDD:304357
		TyrKc	712..996	CDD:197581
Pdgfrl	NP_001011921.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	19..63
		Ig	79..143	CDD:299845	12/56 (21%)
		IG_like	83..>143	CDD:214653	12/56 (21%)
		I-set	272..373	CDD:254352	29/111 (26%)
		Ig	293..372	CDD:299845	24/89 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0200
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900