Protein Alignment btl and F59F5.3

DIOPT Version :10

• Sequence 1: NP_729956.1
• Gene: btl / 39564
• FlyBaseID: FBgn0285896
• Length: 1052
• Species: Drosophila melanogaster
• Sequence 2: NP_509765.2
• Gene: F59F5.3 / 186634
• WormBaseID: WBGene00010342
• Length: 681
• Species: Caenorhabditis elegans
• Alignment Length: 681
• Identity: 139/681 - (20%)
• Similarity: 237/681 - (34%)
• Gaps: 241/681 - (35%)

  Fly   407 LSGNTVNLACP-VYGKANITWTKDKK----PLNRELGVY--VQKNWTLRFVEATSEDSGLYNCKV 464
            |:|..|.|.|. .|...|:...:::|    |.|...|.|  :.:|...||.:....|. |.:.|:
 Worm   152 LNGTGVYLQCSGSYHTENVKLLENQKSLDIPYNPFKGFYIDISRNPINRFYQCEHNDE-LISFKL 215

  Fly   465 CN-AWGCIQFDFSVQINDRTRSAPIIVVPQNQTVK-VNGSLVMKCTVYSDLHPTVSWKRVVLKNA 527
            .| |....:..|.:.:|..|..:.|..|..:|.:| .:.|:::.|       |:.|
 Worm   216 QNMANNGYENKFKMLMNSYTFQSEIQCVFDDQAIKNTHVSVILAC-------PSKS--------- 264

  Fly   528 SLDGLKSVEIQNLNFTVTNDSVVLTLRNVTFDQEGWYTCLASSGLGRSNSSVYLRVV---SPLPP 589
                 |..|:.|                               ...|.:..:|...|   |.:.|
 Worm   265 -----KCPELTN-------------------------------RANRRSHKIYTAFVPKSSNIDP 293

  Fly   590 LEIYALLHAHPLGFTLA---------AITIVALFLLGSAFI----TFMLRRLRREKLLKLRIETV 641
            ...:.:|..:  |.|:|         :.|..||.::|:..|    ..:.:.||:....|
 Worm   294 KSYHCVLIIN--GNTVAEAFLEEADFSTTYYALLIIGAGLILTIFVILTKSLRQNNYNK------ 350

  Fly   642 HQWTKKVIIYRPGGEEGSGCSSGDLQMPVIRIEKQRTTVSTTGTGGTDPAQGFNEYEFPLDSNWE 706
                                                  ||||...                   |
 Worm   351 --------------------------------------VSTTDVR-------------------E 358

  Fly   707 IPRQQLSLGSILGEGAFGRVVMAEAEGLPRSPQLAET---IVAVKMVKEEHTDTDMASLVREMEV 768
            ...::|:..|.||.|....:..||         :.:|   ||..:.|::.|       ..:|:::
 Worm   359 TRIEELNNKSKLGVGNSSTIYTAE---------ICKTKKCIVIKESVRKSH-------CTKELKL 407

  Fly   769 MKMIGKHINIINLLGCCSQGGPLWVIVE------------------YAPHGNLKDFLKQNRPGAP 815
            :|.: ||.|||.         ||.|||:                  |.....|:.::.:..|  |
 Worm   408 LKSL-KHPNIIT---------PLGVIVQPEQKTCFNVQIRQHLLLPYYQKTCLETYIHKFYP--P 460

  Fly   816 QRRSDSDGYLDDKPLISTQHLGEKELTKF-----AFQIARGMEYLASRRCIHRDLAARNVLVSDG 875
            :|..::..:.::..      :.|:|:|.|     |:|:|..:|||......|||:|.||||:|:.
 Worm   461 KRGGNNIFHTNEAT------VPEEEITMFDLVSIAWQVASALEYLKGMEITHRDVAMRNVLISNN 519

  Fly   876 YVMKIADFGLARDIQDT----------EYYRKNTNGRLPIKWMAPESLQEKKYDSQSDVWSYGVL 930
            .|.||.||..|:..:.|          |..:.:.:..:| |....|.|:...|...|:|:.:|.|
 Worm   520 KVCKITDFERAKKGETTRKISIEKKIKEILKAHMSKDIP-KEYPNECLKGVYYYYSSEVYCFGRL 583

  Fly   931 ---LWEIM---TYGDQPYPHILSAEELYSYLITGQRMEKPAKCSLNIYVVMRQCWHFESCARPTF 989
               |:..|   .|| :.||.|                 :|..|...||.::..|.:....:||:.
 Worm   584 MLCLFSFMKPCDYG-RIYPPI-----------------QPENCPKAIYDLIVDCINENRKSRPSI 630

  Fly   990 AELVESFDGILQQASSNPNDAYLDLSMPMLE 1020
            :...:....:|:...   :|.:|.|...:::
 Worm   631 SSCKDVLSTVLKHMD---HDEFLKLKQTLID 658

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
btl	NP_729956.1	Ig	143..215	CDD:472250
		Ig strand B	160..164	CDD:409570
		Ig strand C	175..179	CDD:409570
		Ig strand E	197..201	CDD:409570
		Ig strand F	211..215	CDD:409570
		Ig_3	247..333	CDD:464046
		Ig	398..479	CDD:472250	21/79 (27%)
		Ig strand B	412..416	CDD:409393	2/3 (67%)
		Ig strand C	423..427	CDD:409393	1/3 (33%)
		Ig strand E	445..449	CDD:409393	0/3 (0%)
		Ig strand F	459..464	CDD:409393	1/4 (25%)
		Ig strand G	472..475	CDD:409393	0/2 (0%)
		IG_like	492..583	CDD:214653	11/91 (12%)
		Ig strand B	503..507	CDD:409444	0/3 (0%)
		Ig strand C	516..520	CDD:409444	1/3 (33%)
		Ig strand E	549..553	CDD:409444	0/3 (0%)
		Ig strand F	563..568	CDD:409444	0/4 (0%)
		Ig strand G	576..579	CDD:409444	0/2 (0%)
		Protein Kinases, catalytic domain	700..1000	CDD:473864	80/341 (23%)
F59F5.3	NP_509765.2	PK_Tyr_Ser-Thr	<413..637	CDD:462242	64/259 (25%)