DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment btl and kin-16

DIOPT Version :9

Sequence 1:	NP_001014583.1	Gene:	btl / 39564	FlyBaseID:	FBgn0285896	Length:	1052	Species:	Drosophila melanogaster
Sequence 2:	NP_496017.1	Gene:	kin-16 / 174499	WormBaseID:	WBGene00002200	Length:	495	Species:	Caenorhabditis elegans

Alignment Length:	447	Identity:	132/447 - (29%)
Similarity:	209/447 - (46%)	Gaps:	88/447 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   604 TLAAITIVALFLLGSAFITFMLRRLRREKLLKLRIETVHQWTKKVI---IYRPGGEEGSGCSSGD 665
            |.....:..|.:| .|||.|::.||||.|..:.|        |.:.   ||            .|
Worm    60 TTVFFVVYGLLVL-LAFIAFLVWRLRRSKTQEKR--------KNMALMNIY------------SD 103

  Fly   666 LQMPVIRIEKQRTTVSTTGTGGTDPAQGFN-------EYEFPLDSNWEIPRQQLSLGSILGEGAF 723
            |:                .||...|.:..|       :| .|....:||..:.|...||||.|.|
Worm   104 LR----------------DTGDAMPEELKNRPLNDKLDY-LPYKKQYEIASENLENKSILGSGNF 151

  Fly   724 GRV---VMAEAEGLPRSPQLAETIVAVKMVKEEHTDTDMASLVREMEVMKMIGKHINIINLLGCC 785
            |.|   ::..|.......:.....||||.....:..:..:.|..|:.:|..||:..|::.|:|..
Worm   152 GVVRKGILKMASPKNEEEKKMRLTVAVKSAANCYDISQTSMLAAELRLMCSIGRFPNVLALVGAV 216

  Fly   786 S---QGGPLWVIVEYAPHGNLKDFLKQNR-------------------PGAPQRRS--------D 820
            :   :.|.|.::.||...|:::.:|..:|                   |.:.:|::        :
Worm   217 TSELRKGRLLIVTEYIDCGDIRKYLIDHRNVFQDHLIEDKTEPDSYLTPISAKRKNYVFKNTDEN 281

  Fly   821 SDGYLDDKPLISTQHLGEKELTKFAFQIARGMEYLASRRCIHRDLAARNVLVSDGYVMKIADFGL 885
            ||..:.:    |...|...:|..|..|||.||:||||...:|||||.||||:.....::|||||:
Worm   282 SDYVIKE----SLDSLTTSDLLSFGLQIANGMQYLASIPMVHRDLALRNVLLKKNKTIRIADFGM 342

  Fly   886 ARDIQDTEYY--RKNTNGRLPIKWMAPESLQEKKYDSQSDVWSYGVLLWEIMTYGDQPYPHILSA 948
            ||..::..||  :|..:..:|::||:||:....|:..:|||||:|:.|:||.|.|..|||.:.|
Worm   343 ARTHENKSYYIPQKTKDAPVPVRWMSPEAFDTMKFTEKSDVWSFGICLYEIFTLGQLPYPDVPS- 406

  Fly   949 EELYSYLITGQRMEKPAKCSLNIYVVMRQCWHFESCARPTFAELVESFDGILQQASS 1005
            |.:|.|:.:|:|..:|..|.:.:|.:|:.|||.:...||.|:..||.|.|.:::::|
Worm   407 ERIYEYMHSGRRCPQPQHCHVELYDLMKLCWHEKPELRPNFSNCVEYFIGHMKKSAS 463

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
btl	NP_001014583.1	IG_like	149..232	CDD:214653
		IGc2	157..215	CDD:197706
		IG	247..336	CDD:214652
		Ig	258..340	CDD:143165
		I-set	394..479	CDD:254352
		IGc2	408..469	CDD:197706
		IG_like	492..583	CDD:214653
		Ig	507..583	CDD:299845
		PKc_like	700..1000	CDD:304357	108/334 (32%)
		TyrKc	712..996	CDD:197581	103/318 (32%)
kin-16	NP_496017.1	STYKc	140..454	CDD:214568	103/318 (32%)
kin-16	NP_496017.1	PTKc	145..454	CDD:270623	101/313 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0200
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24416
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910