DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment btl and W04G5.10

DIOPT Version :9

Sequence 1:	NP_001014583.1	Gene:	btl / 39564	FlyBaseID:	FBgn0285896	Length:	1052	Species:	Drosophila melanogaster
Sequence 2:	NP_492969.2	Gene:	W04G5.10 / 173049	WormBaseID:	WBGene00012270	Length:	412	Species:	Caenorhabditis elegans

Alignment Length:	427	Identity:	137/427 - (32%)
Similarity:	196/427 - (45%)	Gaps:	88/427 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   589 PLEIYALLHAHPLGFTLAAITIVALFLLGSAFITFMLRRLRREKLLKLRIETVHQWTKKVIIYRP 653
            |:.||              |..|.|||..|.|:.::.||:               .|........
Worm     8 PIFIY--------------IIFVLLFLALSLFLLYIWRRI---------------LTNSSNSDLG 43

  Fly   654 GGEEGSGCSSGDLQMPV--------IRIEKQRTTVSTT-----GTGGTDPAQGFNEYEFPLDSNW 705
            |.||....|.....:|:        .||:.:...:|.|     |                 |::.
Worm    44 GSEEDVERSLLTTSLPISNKYDLDRTRIQTESELISETIKSLIG-----------------DNHL 91

  Fly   706 EIPRQQLSLG--SILGEGAFGRVVMAEAEGLPRSPQLAETIVAVKMVKEEHTDTDMASLVREMEV 768
            ||..:.|.:.  :.:|.|.||.|..||.....|:...  .|||||.....|.......|..|:.|
Worm    92 EIDPENLKISTENYIGSGFFGTVYRAELRRERRNSNF--MIVAVKEPSNIHNIRQKKILHEELNV 154

  Fly   769 MKMIGKHINIINLLGCCSQGGPLWVIVEYAPHGNLKDFLKQNRPGAPQRRSDSDGY-LDDKPLIS 832
            |..:.||.||::|:|..:|.. :.::.||...|:|..||:       :.:.|.|.. ||:|.|.
Worm   155 MCSMEKHPNILSLVGVVTQRN-VMIVTEYVEDGDLLKFLR-------KCKFDKDSVKLDEKSLC- 210

  Fly   833 TQHLGEKELTKFAFQIARGMEYLASRRCIHRDLAARNVLVSDGYVMKIADFGLARDIQDTEYYR- 896
                 :.:|..|.||||.||:||....|:|||||.||||:.:..|:|||||||||.....:|||
Worm   211 -----KADLFSFTFQIANGMQYLERVPCVHRDLALRNVLIKNNGVLKIADFGLARRHDKKDYYRT 270

  Fly   897 KNTNGRLPIKWMAPESLQEK----KYDSQSDVWSYGVLLWEIMTYGDQPYPHILS-----AEELY 952
            |.|:..|||||:|||..:|:    ::||:||||||||.|:||.:.|:.||..:.|     .:.|.
Worm   271 KTTDTALPIKWLAPECFEEEEEKIRFDSKSDVWSYGVCLYEIFSLGESPYNELDSNNFAFLQVLA 335

  Fly   953 SYLITGQRMEKPAKCSLNIYVVMRQCWHFESCARPTF 989
            .:|..|..:.:|..|:..:|..|:.||:.....||:|
Worm   336 DFLRKGNTLSEPEHCAPKMYYFMKSCWNLIPEERPSF 372

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
btl	NP_001014583.1	IG_like	149..232	CDD:214653
		IGc2	157..215	CDD:197706
		IG	247..336	CDD:214652
		Ig	258..340	CDD:143165
		I-set	394..479	CDD:254352
		IGc2	408..469	CDD:197706
		IG_like	492..583	CDD:214653
		Ig	507..583	CDD:299845
		PKc_like	700..1000	CDD:304357	114/303 (38%)
		TyrKc	712..996	CDD:197581	111/291 (38%)
W04G5.10	NP_492969.2	PTKc	104..378	CDD:270623	110/285 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0200
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810