Protein Alignment btl and tec

DIOPT Version :10

• Sequence 1: NP_729956.1
• Gene: btl / 39564
• FlyBaseID: FBgn0285896
• Length: 1052
• Species: Drosophila melanogaster
• Sequence 2: XP_031751261.1
• Gene: tec / 100491653
• XenbaseID: XB-GENE-6076361
• Length: 648
• Species: Xenopus tropicalis
• Alignment Length: 708
• Identity: 159/708 - (22%)
• Similarity: 252/708 - (35%)
• Gaps: 235/708 - (33%)

  Fly   428 KDKKPLNRELGVYVQKNWTLRFVEATSEDSGLYNCKVCNAWGCIQFDFSVQINDRTRSAPIIVVP 492
            |...|||.:..|:|.....|.:.|...|..............|::|
 Frog    39 KRTSPLNYKERVFVLTKSRLTYYEGRPEKKNKKGSVDITKVKCVEF------------------- 84

  Fly   493 QNQTVKVNGSLVMKC-------------TVYSDLHPTV----SWKRVVLKNASLDGLKSVEIQNL 540
                || |||..:.|             |:|. ..||.    .|.:::.:.
 Frog    85 ----VK-NGSENIPCQYKYAFQIVYESNTLYV-FAPTAESRFKWVKLIKEE-------------- 129

  Fly   541 NFTVTNDSVVLTLRNVTFDQEGWYTC-------------------LASSGLGRSNSSVYLRVVSP 586
               |.|:|.:::..:..|..:|.|.|                   :....|..:..::..|...|
 Frog   130 ---VKNNSFIMSKYHPQFWADGVYQCCRQTEKLAPGCEEYNLFGDITKKPLPPTPDAIRARPPPP 191

  Fly   587 LPP---------LEIYALLHAHPL-GFTLAAITIVALFLL--------------------GSAFI 621
            .||         ..:.|:...||: ...|..:|....|:|                    .|.::
 Frog   192 RPPDPEPEDNGEETVIAMFDFHPVEPHDLRLVTGEEYFVLEKKDAHWWKARNTYGQQGYIPSNYV 256

  Fly   622 TFM--------------LRRLRREKLLKLR---------------IETVHQWTKKVIIYRPGGEE 657
            |..              :.|.:.|:|||..               :.||..:||.       |.|
 Frog   257 TEKKLDNLYQYEWYSRNMNRSKAEQLLKSEDKEGGFIVRNSSQAGLYTVSLYTKY-------GGE 314

  Fly   658 GSGC------------------------------------SSG---DLQMPVIRIEKQRTTVSTT 683
            ||.|                                    ::|   .|:.||  ..|.::..:|.
 Frog   315 GSTCIRHYHIKETQYPKKYYLAEKHVFNTIPEMIEYHKHNAAGLVTRLRYPV--CSKNKSAPTTA 377

  Fly   684 GTGGTDPAQGFNEYEFPLDSNWEIPRQQLSLGSILGEGAFGRVVMAEAEGLPRSPQLAETIVAVK 748
            |              |..| .|||...:|:....||.|.||.|.:.:..        |:..||:|
 Frog   378 G--------------FSYD-KWEINPSELTFMKELGSGLFGVVRLGKWR--------AQYKVAIK 419

  Fly   749 MVKEEHTDTDMASLVREMEVMKMIGKHINIINLLGCCSQGGPLWVIVEYAPHGNLKDFLKQNRPG 813
            .::|.....:  ..:.|.:||..: .|:.::.|.|.|:|..|::::.|:..||.|.::|:|..
 Frog   420 AIREGAMSEE--DFIEEAKVMMKL-THLKLVQLYGVCTQQRPIYIVTEFMEHGCLLNYLRQRH-- 479

  Fly   814 APQRRSDSDGYLDDKPLISTQHLGEKELTKFAFQIARGMEYLASRRCIHRDLAARNVLVSDGYVM 878
                     |......|:|           ....:...|.||.....|||||||||.||:|..|:
 Frog   480 ---------GQFSPDILLS-----------MCQDVCEAMSYLEQNNFIHRDLAARNCLVNDAGVV 524

  Fly   879 KIADFGLARDIQDTEYYRKNTNGRLPIKWMAPESLQEKKYDSQSDVWSYGVLLWEIMTYGDQPYP 943
            |::|||:.|.:.| :.|..:...:.|:||..||.....::.|:|||||:|||:||:.|.|..|:
 Frog   525 KVSDFGMTRYVLD-DQYTSSCGAKFPVKWSPPEVFNYSRFSSKSDVWSFGVLMWEVFTEGKMPF- 587

  Fly   944 HILSAEELYSYLITGQRMEKPAKCSLNIYVVMRQCWHFESCARPTFAELVESFDGILQ 1001
            ...|..|:...:..|:|:.:|...:..||.||..|||.:...||.|.:|::....||:
 Frog   588 ESYSNVEVVEMVTRGERLYRPKLATKIIYSVMVACWHEKPEGRPKFFDLMKQIGLILE 645

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
btl	NP_729956.1	Ig	143..215	CDD:472250
		Ig strand B	160..164	CDD:409570
		Ig strand C	175..179	CDD:409570
		Ig strand E	197..201	CDD:409570
		Ig strand F	211..215	CDD:409570
		Ig_3	247..333	CDD:464046
		Ig	398..479	CDD:472250	11/50 (22%)
		Ig strand B	412..416	CDD:409393
		Ig strand C	423..427	CDD:409393
		Ig strand E	445..449	CDD:409393	1/3 (33%)
		Ig strand F	459..464	CDD:409393	0/4 (0%)
		Ig strand G	472..475	CDD:409393	1/2 (50%)
		IG_like	492..583	CDD:214653	19/126 (15%)
		Ig strand B	503..507	CDD:409444	0/3 (0%)
		Ig strand C	516..520	CDD:409444	1/7 (14%)
		Ig strand E	549..553	CDD:409444	0/3 (0%)
		Ig strand F	563..568	CDD:409444	2/23 (9%)
		Ig strand G	576..579	CDD:409444	0/2 (0%)
		Protein Kinases, catalytic domain	700..1000	CDD:473864	92/299 (31%)
tec	XP_031751261.1	PH_Btk	27..168	CDD:269944	29/170 (17%)
		SH3_Tec	204..259	CDD:212838	9/54 (17%)
		SH2_Tec_Itk	262..368	CDD:198259	18/114 (16%)
		PTKc_Tec_Rlk	386..645	CDD:270685	90/293 (31%)