DRSC/TRiP Functional Genomics Resources

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Protein Alignment Frl and FHDC1

DIOPT Version :10

Sequence 1:NP_729954.2 Gene:Frl / 39561 FlyBaseID:FBgn0267795 Length:1183 Species:Drosophila melanogaster
Sequence 2:NP_203751.2 Gene:FHDC1 / 85462 HGNCID:29363 Length:1143 Species:Homo sapiens


Alignment Length:36 Identity:11/36 - (30%)
Similarity:17/36 - (47%) Gaps:5/36 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly    43 FDVIKKEMECIVKEDPRNAAIIIRLHFH---DCFVQ 75
            ||.:|::|:......|....:.:  ||.   |||.|
Human   222 FDTVKRKMQAQSPYLPHYGGVDV--HFSGAADCFRQ 255

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
FrlNP_729954.2 Drf_GBD 77..371 CDD:461886
Drf_FH3 374..567 CDD:461885
FH2 687..1063 CDD:396655
FHDC1NP_203751.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 16..89
FH2 93..457 CDD:396655 11/36 (31%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 517..638
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 706..1143
PHA03307 730..>1136 CDD:223039
MTBD, microtubule-binding domain. /evidence=ECO:0000269|PubMed:18815276 960..1086
Blue background indicates that the domain is not in the aligned region.

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