DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Frl and AT5G48360

DIOPT Version :9

Sequence 1:	NP_729954.2	Gene:	Frl / 39561	FlyBaseID:	FBgn0267795	Length:	1183	Species:	Drosophila melanogaster
Sequence 2:	NP_199647.2	Gene:	AT5G48360 / 834889	AraportID:	AT5G48360	Length:	782	Species:	Arabidopsis thaliana

Alignment Length:	622	Identity:	129/622 - (20%)
Similarity:	227/622 - (36%)	Gaps:	153/622 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   546 RMLQHNEQELKKRDTLLHTKNMELQTLSRSLPRSASSGDGSLANGGLMAGSTSGAASLTLPPPPP 610
            |...||..|.:..:.....:.....:...|||.||:|......:.. .:|..|.|.|.::...||
plant   204 RSFHHNNYETEVNEEDEEEEEDVFFSPMASLPGSANSSPSHSCSSS-CSGWVSPARSFSITMSPP 267

  Fly   611 PMPASPTASSAAPPPP------------------------------PPPAPPAPPPPPGFSPLGS 645
            ....|...:..:|.|.                              |..:..:..|..||  :.:
plant   268 NPRYSDATNLQSPSPERLRVRKNYNGNGSSSLRMFSFWNQNMGFGFPRISSASTSPDRGF--IRT 330

  Fly   646 PSGSLASTAPSPP---------HAPPMLSSF---------------------------------- 667
            |..||.|:..:.|         .:||:.:.|
plant   331 PLSSLYSSVSTSPDGLFRKFLDSSPPIWNDFSRNVKSVLLSHTASSRRDFVINIGESSSQQSKVP 395

  Fly   668 ------QPPP--PPVAGFMPAPDGAMTIKRKVPTKYKLPTLNWIALKPNQVRGTIFNELDDEKIF 724
                  :|||  ||...|:...|    :|::..:......|:|..|:.:           ..|:.
plant   396 ALPPPTRPPPLVPPSQPFVVQND----VKKQSFSDQPPKQLHWERLRSS-----------SSKLS 445

  Fly   725 KQIDFNEFEERFKIGIGGALRNGSNGTEVDGSLQSSKRFKRPDNVSLLEHTRLRNIAISRRKLGM 789
            |::    .|..|       :.|.||..::            |....:|:..:.:|||...:.|.:
plant   446 KEM----VETMF-------IANSSNPRDL------------PIQNQVLDPRKAQNIATLLQLLNL 487

  Fly   790 PIDDVIAAIHSLDLKKLSLENVELLQKMVPTDAEVKSYKEYIIERKDQQLLTEEDKFMLQLSRVE 854
            ...||..|:...|...|..|.:|.|.::.|:..|.:..|.:    .|...:...::|:.:|..|.
plant   488 STKDVCQALLDGDCDVLGAELLECLSRLAPSKEEERKLKSF----SDGSEIGPAERFLKELLHVP 548

  Fly   855 RISSKLAIMNYMGNFVDSVHLISPQVQSIAGASTSLKQSRKFKAVLEIVLAFGNYLN--SNKRGP 917
            .:..::..:.::.||...:..:......:..|...|:.||.|..:||.:|..||.::  :|:.|.
plant   549 FVFKRVDALLFVANFHSEIKRLRKSFSVVQVACEELRNSRMFSILLEAILKTGNMMSVRTNRCGD 613

  Fly   918 AYGFKLQSLDTLIDTKSTDKRSSLLHYIV-------ATIRAKFPELLNFESELYGTDKAASVALE 975
            |..|||.:|..|:|.|..|.||||||::|       .::|| ...:.|..:||....|:|.:...
plant   614 ADAFKLDTLLKLVDVKGLDGRSSLLHFVVQEMMKSEGSVRA-LEGIRNLNTELSNVKKSADIEYG 677

  Fly   976 NVVADVQELEKGMD------LVRKEAE------LRVKGAQTHILRDFLNNSEDKLKKIKSDLRHA 1028
            .:.::|..:.:|:.      |:.:|:.      |:.|...|.    ||..:.:::.|||......
plant   678 VLRSNVSRICQGLKNIEALLLLSEESGSYGDQWLKFKERMTR----FLKTAAEEIVKIKIRESST 738

  Fly  1029 QEAFKECVEYF-GDSSRNADAAAFFALIVRFTRAFKQ 1064
            ..|.:|..|.| ||:|:.......|.::..|.....|
plant   739 LSALEEVTEQFHGDASKEGHTMRIFMIVRDFLSVLDQ 775

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Frl	NP_729954.2	Drf_GBD	77..371	CDD:283920
		Drf_FH3	374..567	CDD:283917	4/20 (20%)
		FH2	687..1063	CDD:280362	90/397 (23%)
AT5G48360	NP_199647.2	FH2	430..774	CDD:396655	89/386 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	116	1.000	Inparanoid score	I2015
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.960