Protein Alignment Frl and AFH1

DIOPT Version :9

• Sequence 1: NP_729954.2
• Gene: Frl / 39561
• FlyBaseID: FBgn0267795
• Length: 1183
• Species: Drosophila melanogaster
• Sequence 2: NP_189177.1
• Gene: AFH1 / 822136
• AraportID: AT3G25500
• Length: 1051
• Species: Arabidopsis thaliana
• Alignment Length: 672
• Identity: 166/672 - (24%)
• Similarity: 270/672 - (40%)
• Gaps: 133/672 - (19%)

  Fly   482 SETKTSALERVQELEDQLEREIDRNSEFLYKYAELESESLTLKTEREQLAMIRQKLEEELTVMQR 546
            |.|.||...|..:..:...|....:|.....|...:.....|..   .::.:||.|:.:|.....
plant   381 SSTSTSPERRPNDTPEAYLRSPSHSSASTSPYRCFQKSPEVLPA---FMSNLRQGLQSQLLSSPS 442

  Fly   547 MLQHNEQELKKRDTLLHTKNMELQTLSRSLPRSASSGDGSLANGGLMAG----------STSGAA 601
            .....:..||:.|.|            ||  ||.||...|:.:....|.          |:..:.
plant   443 NSHGGQGFLKQLDAL------------RS--RSPSSSSSSVCSSPEKASHKSPVTSPKLSSRNSQ 493

  Fly   602 SLTLPPP---PPPMPASPTASSAAP-------PPPPPPAPPAP-----------------PP--- 636
            ||:..|.   ...:..||..|:.:|       ||||||.||.|                 ||
plant   494 SLSSSPDRDFSHSLDVSPRISNISPQILQSRVPPPPPPPPPLPLWGRRSQVTTKADTISRPPSLT 558

  Fly   637 PPGFSPLGSPSGSLASTAPSPPHAPPMLSSFQPPPPPVAGFMPAPDGAMTIKRKVPTKYKLPTLN 701
            ||. .|...||.:|..|: ||...|..:.:.:     .|...|.|              ||..|:
plant   559 PPS-HPFVIPSENLPVTS-SPMETPETVCASE-----AAEETPKP--------------KLKALH 602

  Fly   702 WIALKPNQVRGTIFNELDDEKIFKQIDFNEFEERFKIGIGGALRNGSNGTEVDGSLQSSKRFKRP 766
            |..::.:..|..:::.|.... || :|....|..|   :..:|.|..|.:      |::.|...|
plant   603 WDKVRASSDREMVWDHLRSSS-FK-LDEEMIETLF---VAKSLNNKPNQS------QTTPRCVLP 656

  Fly   767 ----DNVSLLEHTRLRNIAISRRKLGMPIDDVIAAIHSLDLKKLSLENVELLQKMVPTDAEVKSY 827
                :| .:|:..:.:||||..|.|.:.|::|..|:...:...|..|.:|.|.||.||..|.:..
plant   657 SPNQEN-RVLDPKKAQNIAILLRALNVTIEEVCEALLEGNADTLGTELLESLLKMAPTKEEERKL 720

  Fly   828 KEYIIERKDQQL-LTEEDKFMLQLSRVERISSKLAIMNYMGNFVDSVHLISPQVQSIAGASTSLK 891
            |.|   ..|..: |...:||:..:..:.....::..|.|:.||...|..:....:::..|...|:
plant   721 KAY---NDDSPVKLGHAEKFLKAMLDIPFAFKRVDAMLYVANFESEVEYLKKSFETLEAACEELR 782

  Fly   892 QSRKFKAVLEIVLAFGNYLN-SNKRGPAYGFKLQSLDTLIDTKSTDKRSSLLHYIV-ATIRAKFP 954
            .||.|..:||.||..||.:| ...||.|:.|||.:|..|:|.|..|.:::|||::| ..|||:..
plant   783 NSRMFLKLLEAVLKTGNRMNVGTNRGDAHAFKLDTLLKLVDVKGADGKTTLLHFVVQEIIRAEGT 847

  Fly   955 EL--------------LNFE------SELYGTDKAASVALENVVADVQELEKGMDLVRKEAELRV 999
            .|              |..:      |||....|||::..|.:.:.|.:|.:|:..:.:..:::.
plant   848 RLSGNNTQTDDIKCRKLGLQVVSSLCSELSNVKKAAAMDSEVLSSYVSKLSQGIAKINEAIQVQS 912

  Fly  1000 KGAQ-------THILRDFLNNSEDKLKKIKSDLRHAQEAFKECVEYFGDSSRNADAAAF-FALIV 1056
            ...:       :..::.||..:|:::.::::....|....||..|||..:|...:|..| ..|:|
plant   913 TITEESNSQRFSESMKTFLKRAEEEIIRVQAQESVALSLVKEITEYFHGNSAKEEAHPFRIFLVV 977

  Fly  1057 R-----FTRAFKQHDQENEQRL 1073
            |     ..|..|:....||:.:
plant   978 RDFLGVVDRVCKEVGMINERTM 999

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Frl	NP_729954.2	Drf_GBD	77..371	CDD:283920
		Drf_FH3	374..567	CDD:283917	17/84 (20%)
		FH2	687..1063	CDD:280362	106/415 (26%)
AFH1	NP_189177.1	FH2	591..985	CDD:396655	107/422 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	116	1.000	Inparanoid score	I2015
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.960