DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Frl and AT3G07540

DIOPT Version :9

Sequence 1:	NP_729954.2	Gene:	Frl / 39561	FlyBaseID:	FBgn0267795	Length:	1183	Species:	Drosophila melanogaster
Sequence 2:	NP_566311.1	Gene:	AT3G07540 / 819943	AraportID:	AT3G07540	Length:	841	Species:	Arabidopsis thaliana

Alignment Length:	502	Identity:	114/502 - (22%)
Similarity:	185/502 - (36%)	Gaps:	134/502 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   598 SGAASLTLPPPPPPMPASPTASSAAPPPPPPPAPPAPPP--PPGFSPLGSPSGSLASTAPSPPHA 660
            |.||::|||                ||..||||.|.|||  ||..|.:...||...|.:.
plant   419 SAAAAVTLP----------------PPQRPPPAMPEPPPLVPPSQSFMVQKSGKKLSFSE----- 462

  Fly   661 PPMLSSFQPPPPPVAGFMPAPDGAMTIKRKVPTKYKLPTLNWIALKPNQVRGTIFNELDDEKIFK 725
                             :|...|..|..|..|   ||..|.|..::|:..|...::.|.
plant   463 -----------------LPQSCGEGTTDRPKP---KLKPLPWDKVRPSSRRTNTWDRLP------ 501

  Fly   726 QIDFNEFEERFKIGIGGALRNGSNGTEVDGSL--------QSSKRFKRPDNVSLLEHTRLRNIAI 782
                               .|.||......||        |.||         :|:..:.:|:|:
plant   502 -------------------YNSSNANSKQRSLSCDLPMLNQESK---------VLDPRKSQNVAV 538

  Fly   783 SRRKLGMPIDDVIAAIHSLDLKKLSLENVELLQKMVPTDAEVKSYKEYIIERKDQQL--LTEEDK 845
            ....|.:..:||..|:.......|.:|.:|.|.::.|::.|.|.    :|...|..:  |...::
plant   539 LLTTLKLTTNDVCQALRDGHYDALGVELLESLARVAPSEEEEKK----LISYSDDSVIKLAPSER 599

  Fly   846 FMLQLSRVERISSKLAIMNYMGNFVDSVHLISPQVQSIAGASTSLKQSRKFKAVLEIVLAFGNYL 910
            |:.:|..|..:..::..:..:.:|...|..:......|..|..:|:.||....::...|..|
plant   600 FLKELLNVPFVFKRVDALLSVASFDSKVKHLKRSFSVIQAACEALRNSRMLLRLVGATLEAG--- 661

  Fly   911 NSNKRGPAYGFKLQSLDTLIDTKSTDKRSSLLHYIVATIRAK-----FPELLNFESELYGTDKAA 970
              .|.|.|:.|||::|..|:|.||:|.|:|:|..:|..|...     ...:.|..|.|....|:|
plant   662 --MKSGNAHDFKLEALLGLVDIKSSDGRTSILDSVVQKITESEGIKGLQVVRNLSSVLNDAKKSA 724

  Fly   971 ----SVALENVVADVQELEKGMDLVR----------------KEAELRVKGAQTHILRDFLNNSE 1015
                .|...||....:|::|..:::|                :|:..|           ||..:.
plant   725 ELDYGVVRMNVSKLYEEVQKISEVLRLCEETGHSEEHQWWKFRESVTR-----------FLETAA 778

  Fly  1016 DKLKKIKSDLRHAQEAFKECVEYF--GDSSRNADAAAFFALIVRFTR 1060
            :::|||:.:......|.|:..|||  ..:...|.....|.::..|.:
plant   779 EEIKKIEREEGSTLFAVKKITEYFHVDPAKEEAQLLKVFVIVRDFLK 825

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Frl	NP_729954.2	Drf_GBD	77..371	CDD:283920
		Drf_FH3	374..567	CDD:283917
		FH2	687..1063	CDD:280362	89/411 (22%)
AT3G07540	NP_566311.1	FH2	470..835	CDD:214697	90/413 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	116	1.000	Inparanoid score	I2015
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.960