DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Frl and AT2G43800

DIOPT Version :9

Sequence 1:	NP_729954.2	Gene:	Frl / 39561	FlyBaseID:	FBgn0267795	Length:	1183	Species:	Drosophila melanogaster
Sequence 2:	NP_181908.1	Gene:	AT2G43800 / 818984	AraportID:	AT2G43800	Length:	894	Species:	Arabidopsis thaliana

Alignment Length:	557	Identity:	136/557 - (24%)
Similarity:	221/557 - (39%)	Gaps:	139/557 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   596 STSGAASLTLPPP--PPPMPASPTAS----SAAPPPP-----------PPPAPPAPPPPPGFSPL 643
            |.:|:.|.:..|.  .|.:.|||..|    |.:||..           |....||.||||
plant   353 SINGSGSNSCSPTNFAPSLNASPGTSLKPKSISPPVSLHSQISSNNGIPKRLCPARPPPP----- 412

  Fly   644 GSPSGSLASTAPSPPHAPPMLSSFQPPPPPVAGFMPA------PDGAMTIKRKVPT-KYKLPTLN 701
                                     |||||....:||      |......::||.| |.||.||:
plant   413 -------------------------PPPPPQVSEVPATMSHSLPGDDSDPEKKVETMKPKLKTLH 452

  Fly   702 WIALKPNQVRGTIFNELDDEKIFKQIDFNEFEERFKIGIGGALRNGSNGTEVDGSLQSSKRFKRP 766
            |..::.:..|..:::::.....  |::....|..||:       |.......||.:||..:..|
plant   453 WDKVRASSSRVMVWDQIKSNSF--QVNEEMIETLFKV-------NDPTSRTRDGVVQSVSQENR- 507

  Fly   767 DNVSLLEHTRLRNIAISRRKLGMPIDDVIAAIHSLDLKKLSLENVELLQKMVPTDAEVKSYKEYI 831
                .|:..:..||||..|.|.:..|:|..|:...:...|..|.:|.|.||.||..|....||.
plant   508 ----FLDPRKSHNIAILLRALNVTADEVCEALIEGNSDTLGPELLECLLKMAPTKEEEDKLKEL- 567

  Fly   832 IERKDQ-----QLLTEEDKFMLQLSRVERISSKLAIMNYMGNFVDSVHLISPQVQSIAGASTSLK 891
               ||.     ..:...:||:..|..:.....::..|.|:..|...:..::....::..|:..||
plant   568 ---KDDDDGSPSKIGPAEKFLKALLNIPFAFKRIDAMLYIVKFESEIEYLNRSFDTLEAATGELK 629

  Fly   892 QSRKFKAVLEIVLAFGNYLN-SNKRGPAYGFKLQSLDTLIDTKSTDKRSSLLHYIVATIRAKFPE 955
            .:|.|..:||.||..||.:| ...||.|:.|||.:|..|:|.|..|.:::|||::|       .|
plant   630 NTRMFLKLLEAVLKTGNRMNIGTNRGDAHAFKLDTLLKLVDIKGADGKTTLLHFVV-------QE 687

  Fly   956 LLNFE-----------------------------------------SELYGTDKAASVALENVVA 979
            ::.||                                         |:|....|||::...:::.
plant   688 IIKFEGARVPFTPSQSHIGDNMAEQSAFQDDLELKKLGLQVVSGLSSQLINVKKAAAMDSNSLIN 752

  Fly   980 DVQELEKGMDLVRKE-AELRVK-GAQTHI--LRDFLNNSEDKLKKIKSDLRHAQEAFKECVEYFG 1040
            :..|:.:|:..|::. .||:.: |.:..:  :..|||..|.::.:::|...:..:..||..|||
plant   753 ETAEIARGIAKVKEVITELKQETGVERFLESMNSFLNKGEKEITELQSHGDNVMKMVKEVTEYF- 816

  Fly  1041 DSSRNADAAAF--FALIVRFTRAFKQHDQE----NEQ 1071
              ..|::...|  ||::..|.....|..:|    ||:
plant   817 --HGNSETHPFRIFAVVRDFLTILDQVCKEVGRVNER 851

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Frl	NP_729954.2	Drf_GBD	77..371	CDD:283920
		Drf_FH3	374..567	CDD:283917
		FH2	687..1063	CDD:280362	105/429 (24%)
AT2G43800	NP_181908.1	FH2	438..839	CDD:396655	105/428 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	116	1.000	Inparanoid score	I2015
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.960