Protein Alignment Frl and AT2G25050

DIOPT Version :10

• Sequence 1: NP_729954.2
• Gene: Frl / 39561
• FlyBaseID: FBgn0267795
• Length: 1183
• Species: Drosophila melanogaster
• Sequence 2: NP_001318287.1
• Gene: AT2G25050 / 817043
• AraportID: AT2G25050
• Length: 1168
• Species: Arabidopsis thaliana
• Alignment Length: 1049
• Identity: 234/1049 - (22%)
• Similarity: 406/1049 - (38%)
• Gaps: 303/1049 - (28%)

  Fly   296 PSLKRRSRHIAKLNMGAATD--DIHVSIMC--LRAI-------------------------MNNK 331
            ||..|..::|::.|:|:...  |..:::.|  ||.|                         ..:|
plant   177 PSQLRFLQYISRRNVGSQWPPLDQALTLDCVNLRLIPDFDGEGGCRPIFRIYGQDPFMASDRTSK 241

  Fly   332 YGFNM------VIQHREA--------INCIALSLIHKSLRTKALVLELLAAICLVKGGHEIILGS 382
            ..|:|      |.|:::|        |||..|.         .:|||     |       |.|||
plant   242 VLFSMPKRSKAVRQYKQADCELVKIDINCHILG---------DVVLE-----C-------ITLGS 285

  Fly   383 FDNFKDVCQEKRRFQTLMEYFMNFEAFNIDFMVACMQFMN-----IVVHSVEDMNYRVHLQYEFT 442
                 |:.:|:..|:.:         ||..|:.:.:..:|     ::.::.:........:..|:
plant   286 -----DLEREEMMFRVV---------FNTAFLRSNILTLNRGEIDVLWNTTDRFPKDFSAEVIFS 336

  Fly   443 ALGLDKYLERIRLTESEE---------LKVQ----ISAYLDNVFDVAALMEDSETKTSALE---- 490
            .:|..|.|..:.|...||         .|||    .:.:||...|||..:.:..|..:.|:
plant   337 EMGAGKKLASVDLPHMEEKDVLPMEAFAKVQEIFSEAEWLDPNSDVAVTVFNQITAANILQESLD 401

  Fly   491 ----RVQELEDQLEREIDRNSEFLYKYAELESESL-----TLKTEREQLAM-----------IRQ 535
                |..:....||..:::..|   |...:.||::     |...|:|:..|           |.:
plant   402 SGSPRSPDSRSLLESALEKVKE---KTKLMISENIVSSPDTSSPEKEKDTMSSHKSYADPNSILK 463

  Fly   536 KLEE----ELTVMQ---------RMLQ-----------------------HNEQELKKRDTLLH- 563
            |::|    .::|.:         ||:|                       |:........::||
plant   464 KVDESRGLRVSVQRNVHSKIFSPRMVQSPVTSPLPNRSPTQGSPASISRFHSSPSSLGITSILHD 528

  Fly   564 ---TKNME----------------LQTLSRSLPRSAS-----SGDGSLANG--GLMAGSTSGAAS 602
               .|:.|                |..|:.|.|:.||     |.....:||  ...|..||....
plant   529 HGSCKDEESTSSSPASPSISFLPTLHPLTSSQPKKASPQCPQSPTPVHSNGPPSAEAAVTSSPLP 593

  Fly   603 -------LTLPPPPPPMP------ASPTASSAA-------PPPPPPPAP-----------PAPPP 636
                   |:.||||||.|      ::|:.||.:       |||||||.|           |.|||
plant   594 PLKPLRILSRPPPPPPPPPISSLRSTPSPSSTSNSIATQGPPPPPPPPPLQSHRSALSSSPLPPP 658

  Fly   637 PPGFSPLGSPSGSLASTAPSPPHAPPMLSSFQ---------------PPPPPVA--------GFM 678
            .|       |...||:|.|.||..||:.|:.:               ||||..|        ...
plant   659 LP-------PKKLLATTNPPPPPPPPLHSNSRMGAPTSSLVLKSPPVPPPPAPAPLSRSHNGNIP 716

  Fly   679 PAPDGAMTIKRK----------VPTKYKLPTLNWIALKPNQVRGTIFNEL---DDEKIFKQIDFN 730
            |.|...:.:|.:          ...|..|...:|:.| ...|:|:::.|.   |:.......|.:
plant   717 PVPGPPLGLKGRGILQNLKGQGQTRKANLKPYHWLKL-TRAVQGSLWAEAQKSDEAATAPDFDIS 780

  Fly   731 EFEERFKIGIGGALRNGSNGTEVDGSLQSSKRFKRPDNVSLLEHTRLRNIAISRRKLGMPIDDVI 795
            |.|:.|      :..|.|:.:|.:|.....:...:.:.|.|:|..|..|..|...|:.:|:.|::
plant   781 ELEKLF------SAVNLSSDSENNGGKSGRRARPKVEKVQLIELRRAYNCEIMLSKVKIPLPDLM 839

  Fly   796 AAIHSLDLKKLSLENVELLQKMVPTDAEVKSYKEYIIERKDQQLLTEEDKFMLQLSRVERISSKL 860
            :::.:||...:.::.|:.|.|..||..|.:..|.:   ..:::.|...::|.|:|.:|.|:.:||
plant   840 SSVLALDESVIDVDQVDNLIKFCPTKEEAELLKGF---TGNKETLGRCEQFFLELLKVPRVETKL 901

  Fly   861 AIMNYMGNFVDSVHLISPQVQSIAGASTSLKQSRKFKAVLEIVLAFGN----------------- 908
            .:.::...|...|..:...:.:|..|:..::.|.|.|.:::.:|:.||
plant   902 RVFSFKIQFHSQVTDLRRGLNTIHSAANEVRGSAKLKRIMQTILSLGNALNHGTARETLVLFKNL 966

  Fly   909 --------YLNSNKRGPAYGFKLQSLDTLIDTKSTDKRSSLLHYIVATIRAKFPELLNFESELYG 965
                    |::|...|.|.||:|.||..|.||:|.:.:.:|:||:...:..|.||||||..:|..
plant   967 NSLLHFFLYISSLLTGSAIGFRLDSLLKLTDTRSRNSKMTLMHYLCKVLAEKLPELLNFPKDLVS 1031

  Fly   966 TDKAASVALENVVADVQELEKGMDLVRKEAELRVKGAQ--THI---LRDFLNNSEDKLKKIKSDL 1025
            .:.|..:.|:.:..::|.:.||::.|.:|........|  .|.   |::||:.:|.:::.:.|..
plant  1032 LEAATKIQLKYLAEEMQAISKGLEKVVQEFTASETDGQISKHFRMNLKEFLSVAEGEVRSLASLY 1096

  Fly  1026 RHAQEAFKECVEYFGDSSRNADAAAFFALIVRFTRAFKQHDQENEQRLRLEKAAALAASKKENDQ 1090
            .....:......|||:...........:.:..|.|.|.:..:||.:::..||.   .|.|:..::
plant  1097 STVGGSADALALYFGEDPARVPFEQVVSTLQNFVRIFVRSHEENCKQVEFEKK---RAQKEAENE 1158

  Fly  1091 VLMRNKVNQ 1099
            .|.:...|:
plant  1159 KLKKGVYNE 1167

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Frl	NP_729954.2	Drf_GBD	77..371	CDD:461886	24/117 (21%)
		Drf_FH3	374..567	CDD:461885	50/274 (18%)
		FH2	687..1063	CDD:396655	96/418 (23%)
AT2G25050	NP_001318287.1	PTP_DSP_cys	16..189	CDD:475123	4/11 (36%)
		PTEN_C2	197..337	CDD:463081	31/174 (18%)
		FH2	745..1133	CDD:396655	94/397 (24%)