Protein Alignment Frl and fmn2a

DIOPT Version :10

• Sequence 1: NP_729954.2
• Gene: Frl / 39561
• FlyBaseID: FBgn0267795
• Length: 1183
• Species: Drosophila melanogaster
• Sequence 2: XP_001333061.5
• Gene: fmn2a / 793321
• ZFINID: ZDB-GENE-101107-1
• Length: 1465
• Species: Danio rerio
• Alignment Length: 719
• Identity: 179/719 - (24%)
• Similarity: 290/719 - (40%)
• Gaps: 146/719 - (20%)

  Fly   480 EDSET--KTSALE----RVQELEDQLEREIDRNSEFLYKYAELESESLTL-----KTEREQLAMI 533
            :|..|  ..|.||    .:||||..:|       |.|.|.:|:|.::..:     :.:|| :|..
Zfish   782 QDGSTGQSGSVLEGSSVSIQELEQTIE-------ELLEKISEIEKDNHVVDGKLGRKDRE-VAGF 838

  Fly   534 RQKLEEELTVMQRMLQH--------NEQELKKRDTLLHTKNMELQTLSRSLPRSASSGDG----- 585
            .|.:::.....||:|.|        .|:..|....|.|      |:.:..|..||:|..|
Zfish   839 NQTIKQTKVNGQRVLHHVKAIQTSPVEEAFKFPVPLSH------QSQTPKLSDSATSPMGLPYTC 897

  Fly   586 ----------------SLANGGLMAGSTSGAASLTLPPPPP-P--MPASPTASSAAPPPP----- 626
                            .|.....::|.|....:..:||||| |  :|..|....|.||||
Zfish   898 SCQRTTSQPLSTPPPPQLPPPPPLSGMTPPKPTGVIPPPPPLPGFVPPPPVVGKAPPPPPLPGMV 962

  Fly   627 PPPAPP----APPPPPGF-----SPLGSPSGSLASTAPSPPHAPPMLSSFQPPPPPVAGFMPAPD 682
            |||.||    ||||||.|     .|...|.|    ..|.||..||.:.    ||||..|.  .|.
Zfish   963 PPPPPPLPGMAPPPPPPFPGMTPPPPPPPPG----CGPPPPPLPPGIG----PPPPFMGM--GPP 1017

  Fly   683 G----AMTIKRKVPTKYKLPTLNWIAL----KPNQVRGTIFNELDDEKIFKQIDFNEFEERFKIG 739
            |    ::.:|..:.....:..|.|..:    |.:.....::..:.:    ..:||:||.|.|
Zfish  1018 GMAHESVPLKAVIEPPRPMKPLYWTRIQLHAKKDAKSALVWENVQE----PSVDFDEFVEMF--- 1075

  Fly   740 IGGALRNGSNGTEVDGSLQSSKRFKRPDN-----------VSLLEHTRLRNIAISRRKLGMPIDD 793
                            :..:.|..|:|.:           |.||.:.|.:.:.|....|.:.:.|
Zfish  1076 ----------------AKSAVKEKKKPISDTITKSKAKQVVKLLSNKRSQAVGILMSSLHLDMKD 1124

  Fly   794 VIAAIHSLDLKKLSLENVELLQKMVPTDAEVKSYKEYIIERKDQQL---LTEEDKFMLQLSRVER 855
            :..||..:|...:.||.::.|.:......|:...::::...||::.   |.:.::|:||||.|.:
Zfish  1125 IQNAILKMDCTVVDLETLQALYENRAQKEEMDQIEKHVKSSKDKEKPKPLDKPEQFLLQLSEVPQ 1189

  Fly   856 ISSKLAIMNYMGNFVDSVHLISPQVQSIAGASTSLKQSRKFKAVLEIVLAFGNYLN--SNKRGPA 918
            .|.::..:.:...|.:.|..:..:::::....|:|:..:....:|.:||||||.:|  :..||.|
Zfish  1190 FSERVFCILFQSTFTECVTSVQRKLETLGRVCTALQSGQAVLQILGLVLAFGNIMNGGNRSRGQA 1254

  Fly   919 YGFKLQSLDTLIDTKSTDKRSSLLHYIVATIRAKFPELLNFESELYGTD------KAASVALENV 977
            .||.|..|..|.|.||:|...|||.||||.....|.|....|:..|...      :|:.:..|:.
Zfish  1255 DGFSLDILPKLKDVKSSDNSQSLLSYIVAYYLRHFDEDAGKETCTYPLPEPQDLFQASQMKFEDF 1319

  Fly   978 VADVQELEKGMDLVRKEAELRVKGAQTHILRDFLNNSEDKLKKIKSDLR-------HAQEAFKEC 1035
            ..|:::|.|.::....|.|.....:....|:.|.:..:|.|.|.|::|.       ..|..|.|.
Zfish  1320 QRDLRKLRKDLNACSAEREKVCNISSDEHLQPFKDKMDDFLTKAKTELELQEKQLTDTQRIFLEL 1384

  Fly  1036 VEYFG----DSSRNADAAAFFALIVRFTRAFKQ-HDQENEQRLRLEKAAALAASKKENDQVLMRN 1095
            ..:|.    ...:......||.:...|:..||: ..:||:..|:....||....|:..::.....
Zfish  1385 SVFFSVKPKAGEKEVSPNTFFTVWHEFSSDFKELWKRENKSLLQERLKAAEETFKQAREKATYNV 1449

  Fly  1096 KVNQ 1099
            |..|
Zfish  1450 KPKQ 1453

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Frl	NP_729954.2	Drf_GBD	77..371	CDD:461886
		Drf_FH3	374..567	CDD:461885	27/105 (26%)
		FH2	687..1063	CDD:396655	93/412 (23%)
fmn2a	XP_001333061.5	None