DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Frl and inf2

DIOPT Version :9

Sequence 1:	NP_729954.2	Gene:	Frl / 39561	FlyBaseID:	FBgn0267795	Length:	1183	Species:	Drosophila melanogaster
Sequence 2:	XP_021322927.1	Gene:	inf2 / 792715	ZFINID:	ZDB-GENE-140711-5	Length:	238	Species:	Danio rerio

Alignment Length:	135	Identity:	34/135 - (25%)
Similarity:	72/135 - (53%)	Gaps:	3/135 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly   321 IMCLRAIMNNKYGFNMVIQHREAINCIALSLIHKSLRTKALVLELLAAICLVKG-GHEIILGSFD 384
            :.|:||:||:..|.:.::.:...:..::.:|...:...|..|.|||||:.:... ||.:.|.:.:
Zfish   106 VSCVRAVMNSSAGIHFIVDNEGYVRKLSQALDTSNTMVKKQVFELLAALSMFSSEGHRLALDALE 170

  Fly   385 NFKDVCQEKRRFQTLMEYFMNFEAFNIDFMVACMQFMNIVVHSVEDMNYRVHLQYEFTALGLDKY 449
            ::|.|..::.||..:|....:.:  |:.:||..:..:|.::.|.:.:..|..::.||..|.|.:.
Zfish   171 HYKCVKTQQYRFSVIMNELRSTD--NVPYMVTLLSVINALIFSADGLQQRDKMRKEFIGLQLLQL 233

  Fly   450 LERIR 454
            |.::|
Zfish   234 LPKLR 238

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Frl	NP_729954.2	Drf_GBD	77..371	CDD:283920	14/49 (29%)
		Drf_FH3	374..567	CDD:283917	20/82 (24%)
		FH2	687..1063	CDD:280362
inf2	XP_021322927.1	Drf_GBD	<98..154	CDD:310750	13/47 (28%)
inf2	XP_021322927.1	Drf_FH3	160..>226	CDD:310747	15/67 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910