Protein Alignment Frl and Fnbp4

DIOPT Version :9

• Sequence 1: NP_729954.2
• Gene: Frl / 39561
• FlyBaseID: FBgn0267795
• Length: 1183
• Species: Drosophila melanogaster
• Sequence 2: NP_061298.2
• Gene: Fnbp4 / 55935
• MGIID: 1860513
• Length: 1030
• Species: Mus musculus
• Alignment Length: 579
• Identity: 102/579 - (17%)
• Similarity: 155/579 - (26%)
• Gaps: 315/579 - (54%)

  Fly   474 DVAALMEDSETKTSALERVQELEDQLEREIDRNSEFLYKYAELESESLTLKTEREQLAMIRQK-- 536
            |...:.|.|:.:|...|..::::.||..:::...:..::..||.:   ||.::.|.|.:.||.
Mouse   498 DSEKIDEISDKETEVEESSEKIKVQLAPKVEEEQDLKFQIGELAN---TLTSKFEFLGINRQSIS 559

  Fly   537 ------LEEELTV------------MQRMLQHNEQELKK---------------RDTLLH----- 563
                  |:.|..:            ::|.||...::||:               ||...:
Mouse   560 NFHMLLLQTETRIADWREGALNGNYLKRKLQDAAEQLKQYEINATPKGWSCHWDRDHRRYFYVNE 624

  Fly   564 -------------------TKNMELQTLSR--------SLPRSASSGDGSLANGGLMAGSTSGAA 601
                               ||.:..::|.:        :.|.|..|.:.  ..|.|...|.||..
Mouse   625 QSGESQWEFPDGEEEEESQTKEVRDESLPKLTVKDKTCTDPNSTESSEN--PTGSLCKESFSGQV 687

  Fly   602 S-------------------------LTLPPPPPPMPASPTASSAAPPPPPPPAPPAP------- 634
            |                         |.:||||||.|.||      |||||||.||.|
Mouse   688 SSSLMPLTPFWTLLQSNVPVLQPPLPLEMPPPPPPPPESP------PPPPPPPPPPPPLEDGEIQ 746

  Fly   635 -----------PPPPGFS----------------------------------------------- 641
                       ||.||..
Mouse   747 EVEMEDEGSEEPPAPGTEEDTPLKPSTQTTAVTSQSLVDSTASSPPSNKAVKRKAPEMSTSVVQR 811

  Fly   642 ----------------------------------------------------------------- 641
                                                                             
Mouse   812 SATIGSSPVLYSQSAIAAGHQAVGMAHQAVGMAHQAVSASHAAAAGVGHQARGMSLQSNYLGLAA 876

  Fly   642 ------------PLG--SPS-------GSLASTA---PSPPHAPPMLSSFQPPPPPVAGFMPAP- 681
                        |:|  :||       |::|:.|   |.||..||...:  |||||.|..:|.|
Mouse   877 APALMSYAECSVPIGVTTPSLQPAQARGTMAAPAVVEPPPPPPPPPTPT--PPPPPPAPKVPPPE 939

  Fly   682 -------DGAMTIKRKVPTKYKLPTLNWIALKPNQVRGTIFNELDDEKIFKQIDFNEFEERFKIG 739
                   |.|...|.|:|:..|    .|.:::         .|||:|
Mouse   940 KTRKGKKDKAKKSKTKMPSLVK----KWQSIQ---------RELDEE------------------ 973

  Fly   740 IGGALRNGSNGTEVDGSLQSSKRFKRPDNVSLLEHTRLRN-----------IAISRRKL 787
                  :.|:.:|.|....:.||.:......|:.....||           ..:.|||:
Mouse   974 ------DNSSSSEEDRESTAQKRIEEWKQQQLVSGLAERNANFEALPEDWRARLKRRKM 1026

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Frl	NP_729954.2	Drf_GBD	77..371	CDD:283920
		Drf_FH3	374..567	CDD:283917	26/151 (17%)
		FH2	687..1063	CDD:280362	20/112 (18%)
Fnbp4	NP_061298.2	WW	222..249	CDD:334059
		WW	605..636	CDD:238122	2/30 (7%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167846925
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930