Protein Alignment Frl and shtn3

DIOPT Version :9

• Sequence 1: NP_729954.2
• Gene: Frl / 39561
• FlyBaseID: FBgn0267795
• Length: 1183
• Species: Drosophila melanogaster
• Sequence 2: XP_685212.4
• Gene: shtn3 / 557118
• ZFINID: ZDB-GENE-140106-61
• Length: 655
• Species: Danio rerio
• Alignment Length: 669
• Identity: 143/669 - (21%)
• Similarity: 236/669 - (35%)
• Gaps: 237/669 - (35%)

  Fly   344 INCIALSLIHKSLRTKALVLELLAAI--CL----------------------VKGGHEIILGSFD 384
            :||....|.:.||.::..:.|||.:|  |:                      ||...|.:....:
Zfish    84 LNCENRKLKYLSLSSRPCLDELLPSISDCISLEEEVEQQDHSSDSFSQYKQQVKDLQETVSSLLE 148

  Fly   385 NFKDVC---QEKRR-------------------FQTLMEYFMNFEAFNIDFMVACMQFMNIVVHS 427
            ..|.:.   ||::|                   ::|:.:.....:.||...|||..::.|:
Zfish   149 EKKQLACQLQEQQRQIKELTALREKEQAEMKELYKTIDQQSKTIKRFNRVSMVATTEYENM---- 209

  Fly   428 VEDMNYRVHLQ-------YEFTALGLDKYLERIRLTESEELKVQISAYLDNVFDVAALMEDSETK 485
            .|.::....|:       :|......:...:.:.|.:..:..:|:...|::|.:|        ||
Zfish   210 KEQLDLEQSLRQKAETYAHEMMVKQKEANRQSMILLQQADPSIQLLKALEDVANV--------TK 266

  Fly   486 TSALERVQELEDQLEREIDRNSEFLYKYAELESESLTLKTEREQLAMIRQ--KLEEELTVMQRML 548
            |...||:|..|                      :...|:||.||.|:.:|  :|:.:|.::....
Zfish   267 TLEEERMQHQE----------------------KVKALETELEQCALRKQLVQLQRQLEILDEEK 309

  Fly   549 QHNE---QELKKRDTLLHTKNMELQTLSRSLPRSASSGDGSLANGGLMAGSTSGAASLTLPPP-P 609
            :..|   ||.:|::|:|..|..:||       .:.:|.|           |.||.:..|.||| |
Zfish   310 KETEGRLQEEEKKNTILEEKVKDLQ-------EARTSSD-----------SASGPSPGTAPPPAP 356

  Fly   610 PPMPASPTASSAAPPPPPPPAPPAPPPPPG-FSPLGSPSGSLASTAPSPPHAPPMLSSFQPPPPP 673
            ||.|         |||||||.||.|||||. .:||.|....:..::......|.:..:      |
Zfish   357 PPQP---------PPPPPPPPPPPPPPPPSRCNPLSSLIAIMRKSSKGGKGTPKLEQA------P 406

  Fly   674 VAGFMPAPDGAMTIKRKVPTKYKLPTLNWIALKPNQVRGTIFNE-LDDEKIFKQIDFNEFEERFK 737
            |                                         || :||.|: |.:  ||..||.|
Zfish   407 V-----------------------------------------NEAVDDVKV-KAV--NEMMERIK 427

  Fly   738 IGIGGALRNGSNGTEVDGSLQSSKRFKRPDNVSLLEHTRLRNIAISRRKLGMPIDDVIAAIHSLD 802
            .|:  .||...:        |.:|||                    ..||..|:....||.....
Zfish   428 HGV--VLRPVKS--------QDTKRF--------------------GTKLPSPVTAAAAAAVEEK 462

  Fly   803 LKKLSLENVELLQKMVPTD--------AEVK--SYKEYIIERKDQQLLTEEDKFMLQLSRVERIS 857
            .::.::|.::.:.:.|...        |.||  |..|.|:.|:.:|......:...|||:|.
Zfish   463 HQESAMEELKGILETVKKSPSRGFQEVAHVKKDSELEVILRRRRKQACDTGAEDNGQLSKVS--- 524

  Fly   858 SKLAIMNYMGNFVDSVHLISPQVQSIAGASTSLKQSRKFKAVLEIVLAFGNYLNSNK-RGPAYGF 921
                    ..|.::..|.......:...:|:||..|.:           |:..:|:. |.||  .
Zfish   525 --------SSNSLNGRHSSDSGKDTEGPSSSSLSGSER-----------GSRTSSDSGREPA--V 568

  Fly   922 KLQSLDTLIDTKSTDKRSS 940
            ..||.|:.:::|...:..|
Zfish   569 VQQSSDSGMESKGAAQTDS 587

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Frl	NP_729954.2	Drf_GBD	77..371	CDD:283920	9/28 (32%)
		Drf_FH3	374..567	CDD:283917	43/226 (19%)
		FH2	687..1063	CDD:280362	53/266 (20%)
shtn3	XP_685212.4	SMC_N	34..>337	CDD:330553	57/293 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170592138
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930