Protein Alignment Frl and shtn3

DIOPT Version :10

• Sequence 1: NP_729954.2
• Gene: Frl / 39561
• FlyBaseID: FBgn0267795
• Length: 1183
• Species: Drosophila melanogaster
• Sequence 2: XP_073777939.1
• Gene: shtn3 / 557118
• ZFINID: ZDB-GENE-140106-61
• Length: 729
• Species: Danio rerio
• Alignment Length: 669
• Identity: 139/669 - (20%)
• Similarity: 231/669 - (34%)
• Gaps: 242/669 - (36%)

  Fly   344 INCIALSLIHKSLRTKALVLELLAAI--CL----------------------VKGGHEIILGSFD 384
            :||....|.:.||.::..:.|||.:|  |:                      ||...|.:....:
Zfish   163 LNCENRKLKYLSLSSRPCLDELLPSISDCISLEEEVEQQDHSSDSFSQYKQQVKDLQETVSSLLE 227

  Fly   385 NFKDVC---QEKRR-------------------FQTLMEYFMNFEAFNIDFMVACMQFMNIVVHS 427
            ..|.:.   ||::|                   ::|:.:.....:.||...|||..::.|:
Zfish   228 EKKQLACQLQEQQRQIKELTALREKEQAEMKELYKTIDQQSKTIKRFNRVSMVATTEYENM---- 288

  Fly   428 VEDMNYRVHLQ-------YEFTALGLDKYLERIRLTESEELKVQISAYLDNVFDVAALMEDSETK 485
            .|.::....|:       :|......:...:.:.|.:..:..:|:...|::|.:|        ||
Zfish   289 KEQLDLEQSLRQKAETYAHEMMVKQKEANRQSMILLQQADPSIQLLKALEDVANV--------TK 345

  Fly   486 TSALERVQELEDQLEREIDRNSEFLYKYAELESESLTLKTEREQLAMIRQ--KLEEELTVMQRML 548
            |...||:|..|                      :...|:||.||.|:.:|  :|:.:|.::....
Zfish   346 TLEEERMQHQE----------------------KVKALETELEQCALRKQLVQLQRQLEILDEEK 388

  Fly   549 QHNE---QELKKRDTLLHTKNMELQTLSRSLPRSASSGDGSLANGGLMAGSTSGAASLTLPPP-P 609
            :..|   ||.:|::|:|..|..:||       .:.:|.|           |.||.:..|.||| |
Zfish   389 KETEGRLQEEEKKNTILEEKVKDLQ-------EARTSSD-----------SASGPSPGTAPPPAP 435

  Fly   610 PPMPASPTASSAAPPPPPPPAPPAPPPPPG-FSPLGSPSGSLASTAPSPPHAPPMLSSFQPPPPP 673
            ||.|         |||||||.||.|||||. .:||.|....:..::......|.:..:      |
Zfish   436 PPQP---------PPPPPPPPPPPPPPPPSRCNPLSSLIAIMRKSSKGGKGTPKLEQA------P 485

  Fly   674 VAGFMPAPDGAMTIKRKVPTKYKLPTLNWIALKPNQVRGTIFNE-LDDEKIFKQIDFNEFEERFK 737
            |                                         || :||.|: |.:  ||..||.|
Zfish   486 V-----------------------------------------NEAVDDVKV-KAV--NEMMERIK 506

  Fly   738 IGIGGALRNGSNGTEVDGSLQSSKRFKRPDNVSLLEHTRLRNIAISRRKLGMPIDDVIAAIHSLD 802
            .|:                                   .||.:.....||..|:....||.....
Zfish   507 HGV-----------------------------------VLRPVKSQDTKLPSPVTAAAAAAVEEK 536

  Fly   803 LKKLSLENVELLQKMVPTD--------AEVK--SYKEYIIERKDQQLLTEEDKFMLQLSRVERIS 857
            .::.::|.::.:.:.|...        |.||  |..|.|:.|:.:|......:...|||:|.
Zfish   537 HQESAMEELKGILETVKKSPSRGFQEVAHVKKDSELEVILRRRRKQACDTGAEDNGQLSKVS--- 598

  Fly   858 SKLAIMNYMGNFVDSVHLISPQVQSIAGASTSLKQSRKFKAVLEIVLAFGNYLNSNK-RGPAYGF 921
                    ..|.::..|.......:...:|:||..|.:           |:..:|:. |.||  .
Zfish   599 --------SSNSLNGRHSSDSGKDTEGPSSSSLSGSER-----------GSRTSSDSGREPA--V 642

  Fly   922 KLQSLDTLIDTKSTDKRSS 940
            ..||.|:.:::|...:..|
Zfish   643 VQQSSDSGMESKGAAQTDS 661

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Frl	NP_729954.2	Drf_GBD	77..371	CDD:461886	9/28 (32%)
		Drf_FH3	374..567	CDD:461885	43/226 (19%)
		FH2	687..1063	CDD:396655	49/266 (18%)
shtn3	XP_073777939.1	None