Protein Alignment Frl and Fnbp4

DIOPT Version :9

• Sequence 1: NP_729954.2
• Gene: Frl / 39561
• FlyBaseID: FBgn0267795
• Length: 1183
• Species: Drosophila melanogaster
• Sequence 2: NP_001013177.3
• Gene: Fnbp4 / 311183
• RGDID: 1309238
• Length: 1021
• Species: Rattus norvegicus
• Alignment Length: 567
• Identity: 103/567 - (18%)
• Similarity: 159/567 - (28%)
• Gaps: 299/567 - (52%)

  Fly   474 DVAALMEDSETKTSALERVQELEDQLEREIDRNSEFLYKYAELESESLTLKTEREQLAMIRQK-- 536
            |...:.|:|:.:....|..::::.|:..:::...:..::..||.:   ||.::.|.|.:.||.
  Rat   497 DSEKINENSDKEAEVEESSEKIKVQIAPKVEEEQDLKFQIGELAN---TLTSKFEFLGINRQSIS 558

  Fly   537 ------LEEELTV------------MQRMLQHNEQELK-------------------KRDTLLHT 564
                  |:.|..:            ::|.||...::||                   :|...::.
  Rat   559 NFHMLLLQTETRIADWREGALNGNYLKRKLQDAAEQLKQYEINATPKGWSCHWDRDHRRYFYVNE 623

  Fly   565 KNMELQ----------------TLSRSLPR------------SASSGDGSLANGGLMAGSTSGAA 601
            ::.|.|                ....|||:            ||.|.:.|  .|.|...|.||..
  Rat   624 QSGESQWEFPDGEEEEESQAQEVRDESLPKLTEKDKTCTDSNSAESSENS--TGSLCKESFSGQV 686

  Fly   602 S-------------------------LTLPPPPPPMPASPTASSAAPPPPPPPAPPAP------- 634
            |                         |.:||||||.|.||      |||||||.||.|
  Rat   687 SSSLMPLTPFWTLLQSNVPVLQPPLPLEMPPPPPPPPESP------PPPPPPPPPPPPLEDGEIQ 745

  Fly   635 -----------PPPPGFS----------------------------------------------- 641
                       ||.||..
  Rat   746 EVEMEDEGSEEPPAPGTEEDTPLKPSTQTTVVTSQSSVDSTASSPPSTKAVKRKAPEISTAVVQR 810

  Fly   642 ----------------------------------------------------------------- 641
                                                                             
  Rat   811 SATIGSSPVLYSQSAIAAGHQAVGMAHQAVSVSHAAAGMGHPTRGMSLQSNYLGLAAAPAILSYA 875

  Fly   642 ----PLG--SPS-------GSLASTA---PSPPHAPPMLSSFQPPPPPVAGFMPAPDGAMTIKRK 690
                |:|  :||       |::|:.|   |.||..||..|:  |||||.|...|.|:.....||:
  Rat   876 ECSVPIGVTTPSLQPAQARGTVAAPAVVEPPPPPPPPPTST--PPPPPPAPKGPPPEKTRKGKRE 938

  Fly   691 --VPTKYKLPTL--NWIALKPNQVRGTIFNELDDEKIFKQIDFNEFEERFKIGIGGALRNGSNGT 751
              ..:|.|:|:|  .|.:::         .|||:|                        :.|:.:
  Rat   939 KAKKSKTKMPSLVKKWQSIQ---------RELDEE------------------------DNSSSS 970

  Fly   752 EVDGSLQSSKRFKRPDNVSLLEHTRLRN-----------IAISRRKL 787
            |.|....:.||.:......|:.....||           ..:.|||:
  Rat   971 EEDRESTAQKRIEEWKQQQLVSGLAERNANFEALPEDWRARLKRRKM 1017

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Frl	NP_729954.2	Drf_GBD	77..371	CDD:283920
		Drf_FH3	374..567	CDD:283917	21/131 (16%)
		FH2	687..1063	CDD:280362	22/116 (19%)
Fnbp4	NP_001013177.3	WW	222..249	CDD:395320
		WW	604..635	CDD:238122	3/30 (10%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166350424
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930