DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6833 and REX4

DIOPT Version :9

Sequence 1:	NP_001189105.1	Gene:	CG6833 / 39559	FlyBaseID:	FBgn0036405	Length:	290	Species:	Drosophila melanogaster
Sequence 2:	NP_014561.1	Gene:	REX4 / 854075	SGDID:	S000005440	Length:	289	Species:	Saccharomyces cerevisiae

Alignment Length:	271	Identity:	101/271 - (37%)
Similarity:	145/271 - (53%)	Gaps:	20/271 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 ANNKNTTDSTKNVVSPQ--HNQRKLQASMERLQVQQVNTSRRAAGSNWMAAAGGGAAAAAGSENQ 90
            |:..|.|.:.||..|.:  .|.:|:..::......|....:|..||..|..........:..|..
Yeast    12 ASESNPTSNGKNKQSNRKIRNVKKVSKTVNVSSTTQYAPRKRKNGSKIMDMVYNMNKEISKHEKD 76

  Fly    91 --DAKATESAP----------------LSKSARMRMKKKAHRNRILAMDCEMVGVGHNTRDDMLA 137
              :.|..|..|                :|:..|:...|.....:.:|||||.||||...::..||
Yeast    77 KLEGKVFEFNPNKANTSTTIKEPVKVGISEDTRINSNKSKEIGKYIAMDCEFVGVGPEGKESALA 141

  Fly   138 RVSIVNRMGHVLLDKYVKPRKEVTDYRTSVSGIRPQDIANGEDFAAVQNEVMKLIHGRILVGHGL 202
            |:||||..|||:||::||||::|.::||.||||:|:.:.|...|...|.:...::.|||||||.|
Yeast   142 RISIVNYFGHVVLDEFVKPREKVVEWRTWVSGIKPEHMKNAITFKEAQKKTADILEGRILVGHAL 206

  Fly   203 RNDLAVLGIRHPFHDIRDTSHYKPLCKLISNTHTPSLKRLTKAVLGQEIQTGEHNSVEDARAAMG 267
            ::||..|.:.||...:||||.:.|..||.:...|||||:||:.||...||.|||:|||||||.|.
Yeast   207 KHDLEALMLSHPKSLLRDTSRHLPFRKLYAKGKTPSLKKLTREVLKISIQEGEHSSVEDARATML 271

  Fly   268 IYNRVAVDWEK 278
            :|.:...::||
Yeast   272 LYKKEKTEFEK 282

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6833	NP_001189105.1	DnaQ	100..>283	CDD:223916	84/179 (47%)
CG6833	NP_001189105.1	REX4_like	118..270	CDD:99847	78/151 (52%)
REX4	NP_014561.1	REX4_like	122..274	CDD:99847	78/151 (52%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157343757
Domainoid	1	1.000	158	1.000	Domainoid score	I877
eggNOG	1	0.900	-	-		E1_COG0847
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	167	1.000	Inparanoid score	I1026
Isobase	1	0.950	-	0	Normalized mean entropy	S1595
OMA	1	1.010	-	-		QHG53331
OrthoFinder	1	1.000	-	-		FOG0004095
OrthoInspector	1	1.000	-	-		oto99906
orthoMCL	1	0.900	-	-		OOG6_102721
Panther	1	1.100	-	-	LDO	PTHR12801
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1084
SonicParanoid	1	1.000	-	-		X2840
TreeFam	1	0.960	-	-
	15	14.740