DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6833 and pan2

DIOPT Version :9

Sequence 1:	NP_001189105.1	Gene:	CG6833 / 39559	FlyBaseID:	FBgn0036405	Length:	290	Species:	Drosophila melanogaster
Sequence 2:	XP_005162402.1	Gene:	pan2 / 792831	ZFINID:	ZDB-GENE-030131-3113	Length:	1206	Species:	Danio rerio

Alignment Length:	228	Identity:	62/228 - (27%)
Similarity:	98/228 - (42%)	Gaps:	59/228 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    97 SAPLSKSARMRMKKKAHRNRILAMDCEMVGVGH----------------NTRDD----------- 134
            |..|::::..|.::|:|...|..|..||..||.                ..|.|
Zfish   943 SVLLTEASLARKQRKSHATFIPLMVSEMPQVGDLVGLDAEFVTLNQEEAELRSDGTKSTIKPSQM 1007

  Fly   135 MLARVSIVNRMGH----VLLDKYVKPRKEVTDYRTSVSGIRPQDI---ANGEDFAAVQNEVMKLI 192
            .:||::.|...|.    ..:|.|:..:::|.||.|..|||:|.|:   .:.:....:::..:||
Zfish  1008 SVARITCVRGQGQNEGVPFIDDYISTQEQVVDYLTQYSGIKPGDLDAKISSKHLTTLKSTYLKL- 1071

  Fly   193 HGRIL-------VGHGLRNDLAVLGIRHPFHDIRDTSH--YKPLCKLISNTHTPSLKRLTKAVLG 248
              |.|       |||||:.|..|:.:..|...:.||.:  :.|..::|      ||:.|....|.
Zfish  1072 --RFLIDTGVRFVGHGLQKDFRVINLMVPKDQVIDTVYLFHMPRKRMI------SLRFLAWYFLD 1128

  Fly   249 QEIQTGEHNSVEDARAAMGIYNRVAVDWEKYLE 281
            ..||...|:|:||||.|:.:|       .||||
Zfish  1129 LNIQGETHDSIEDARTALQLY-------RKYLE 1154

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6833	NP_001189105.1	DnaQ	100..>283	CDD:223916	61/225 (27%)
CG6833	NP_001189105.1	REX4_like	118..270	CDD:99847	51/194 (26%)
pan2	XP_005162402.1	WD40	<204..>295	CDD:295369
		Peptidase_C19P	504..923	CDD:239137
		UCH_1	519..900	CDD:290159
		PAN2_exo	977..1150	CDD:99846	47/188 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910