DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6833 and Rexo1

DIOPT Version :9

Sequence 1:	NP_001189105.1	Gene:	CG6833 / 39559	FlyBaseID:	FBgn0036405	Length:	290	Species:	Drosophila melanogaster
Sequence 2:	XP_011241832.1	Gene:	Rexo1 / 66932	MGIID:	1914182	Length:	1228	Species:	Mus musculus

Alignment Length:	225	Identity:	66/225 - (29%)
Similarity:	96/225 - (42%)	Gaps:	31/225 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    67 RAAGSNW-------MAAAGGGAAAAAGSENQDAKATESAPLSKSARMRMKKKAHRNRILAMDCEM 124
            |.|| .|       .||.|......|....||.:........::.:..:.:.||.. :.|:||||
Mouse  1012 RVAG-GWETQYMCCSAAVGSVGCQVAKQHVQDGRKENLEGFVRTFQKELPEDAHAG-VFALDCEM 1074

  Fly   125 VGVGHNTRDDMLARVSIVNRMGHVLLDKYVKPRKEVTDYRTSVSGIRPQDIANGEDFAAVQNEVM 189
               .:.|....|.||::|:....|:.|.:|||..||.||.|..||:...|:.   |.:....:|.
Mouse  1075 ---SYTTYGLELTRVTVVDTDMQVVYDTFVKPDNEVVDYNTRFSGVTEADLV---DTSITLRDVQ 1133

  Fly   190 KLI-----HGRILVGHGLRNDLAVLGIRHPFHDIRDTSHYKPLCKLISNTHTPSLKRLTKAVLGQ 249
            .::     ...||:||.|.:||..|.:.|  ..:.|||...|  ..:...:..||:.|....|.|
Mouse  1134 AVLLSMFSADTILIGHSLESDLLALKVIH--GTVVDTSVLFP--HRLGLPYKRSLRNLMADYLRQ 1194

  Fly   250 EIQ--TGEHNSVEDARAAMGIYNRVAVDWE 277
            .||  ...|:|.|||.|.|.:     |.|:
Mouse  1195 IIQDNVDGHSSSEDASACMHL-----VIWK 1219

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6833	NP_001189105.1	DnaQ	100..>283	CDD:223916	56/185 (30%)
CG6833	NP_001189105.1	REX4_like	118..270	CDD:99847	52/158 (33%)
Rexo1	XP_011241832.1	PHA03307	150..>461	CDD:223039
		EloA-BP1	794..969	CDD:374185
		REX1_like	1068..1216	CDD:99848	52/162 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0847
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810