Protein Alignment CG6833 and AEN

DIOPT Version :10

• Sequence 1: NP_648689.1
• Gene: CG6833 / 39559
• FlyBaseID: FBgn0036405
• Length: 290
• Species: Drosophila melanogaster
• Sequence 2: XP_054234601.1
• Gene: AEN / 64782
• HGNCID: 25722
• Length: 461
• Species: Homo sapiens
• Alignment Length: 259
• Identity: 97/259 - (37%)
• Similarity: 132/259 - (50%)
• Gaps: 14/259 - (5%)

  Fly    33 TTDSTKNVVSPQHNQRKLQ-----ASMERLQVQQVNTSRRAAGSNWMAAAGGGAAA--AAGSENQ 90
            |..:.|:|:..:|.:|..|     |....||.|.:.:.....||:.:....|.|.|  ||.|..|
Human   154 TIPNAKDVLRKRHKRRSRQHQRFMARKALLQEQGLLSMPPEPGSSPLPTPFGAATATEAASSGKQ 218

  Fly    91 DAKA-TESAPLSKSARMRMKKKAHRNRILAMDCEMVGVGHNTRDDMLARVSIVNRMGHVLLDKYV 154
            ..:| :.|||.|:............::.:|:||||||.|...|...|||.|||:..|.||.|||:
Human   219 CLRAGSGSAPCSRRPAPGKASGPLPSKCVAIDCEMVGTGPRGRVSELARCSIVSYHGDVLYDKYI 283

  Fly   155 KPRKEVTDYRTSVSGIRPQDIANGEDFAAVQNEVMKLIHGRILVGHGLRNDLAVLGIRHPFHDIR 219
            :|...:.||||..|||..|.:.....|...|.|::||:.|:::|||.|.||...|...||....|
Human   284 RPEMPIADYRTRWSGITRQHMRKAVPFQVAQKEILKLLKGKVVVGHALHNDFQALKYVHPRSQTR 348

  Fly   220 DTSHYKPLCKLISNTHT---PSLKRLTKAVLGQEIQTGE--HNSVEDARAAMGIYNRVAVDWEK 278
            ||: |.|........||   .|||.|...:|.::||.|:  |:|||||..||.:|..|.|.||:
Human   349 DTT-YVPNFLSEPGLHTRARVSLKDLALQLLHKKIQVGQHGHSSVEDATTAMELYRLVEVQWEQ 411

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6833	NP_648689.1	REX4_like	118..270	CDD:99847	68/156 (44%)
AEN	XP_054234601.1	DnaQ_like_exo	247..403	CDD:447876	68/156 (44%)