Protein Alignment CG6833 and REXO4

DIOPT Version :10

• Sequence 1: NP_648689.1
• Gene: CG6833 / 39559
• FlyBaseID: FBgn0036405
• Length: 290
• Species: Drosophila melanogaster
• Sequence 2: NP_065118.2
• Gene: REXO4 / 57109
• HGNCID: 12820
• Length: 422
• Species: Homo sapiens
• Alignment Length: 296
• Identity: 109/296 - (36%)
• Similarity: 162/296 - (54%)
• Gaps: 33/296 - (11%)

  Fly     2 SATPRQKQFDMNRSRANNLDSSRSGSANNKNTTDSTKNVVSP-----QHNQRKLQASM------E 55
            |.:...::..:.|::|:..:.      |.|.|.:.|...:.|     :|.:||.:.:.      |
Human   134 SGSKMDRRAPVPRTKASGTEH------NKKGTKERTNGDIVPERGDIEHKKRKAKEAAPAPPTEE 192

  Fly    56 RLQVQQVNTSRRAAGSNWMAAAGGGAAAAAGSENQDAKATESAPLSKSARMRMKKKAH--RNRIL 118
            .:....|:.      ::..||.|..||..|..:...::.:.|..|       :|::|.  ..|.|
Human   193 DIWFDDVDP------ADIEAAIGPEAAKIARKQLGQSEGSVSLSL-------VKEQAFGGLTRAL 244

  Fly   119 AMDCEMVGVGHNTRDDMLARVSIVNRMGHVLLDKYVKPRKEVTDYRTSVSGIRPQDIANGEDFAA 183
            |:||||||||....:.|.|||||||:.|..:.||||||.:.||||||:||||||:::..||:...
Human   245 ALDCEMVGVGPKGEESMAARVSIVNQYGKCVYDKYVKPTEPVTDYRTAVSGIRPENLKQGEELEV 309

  Fly   184 VQNEVMKLIHGRILVGHGLRNDLAVLGIRHPFHDIRDTSHYKPLCKLISNTHTPSLKRLTKAVLG 248
            ||.||.:::.|||||||.|.|||.||.:.||...||||..|||....:.:.. |||:.|::.:||
Human   310 VQKEVAEMLKGRILVGHALHNDLKVLFLDHPKKKIRDTQKYKPFKSQVKSGR-PSLRLLSEKILG 373

  Fly   249 QEIQTGEHNSVEDARAAMGIYNRVAVDWEKYLEKKR 284
            .::|..||.|::||:|||.:|..|..:||.....:|
Human   374 LQVQQAEHCSIQDAQAAMRLYVMVKKEWESMARDRR 409

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6833	NP_648689.1	REX4_like	118..270	CDD:99847	80/151 (53%)
REXO4	NP_065118.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..194		12/65 (18%)
		REX4_like	244..394	CDD:99847	80/150 (53%)