DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6833 and CG12877

DIOPT Version :9

Sequence 1:	NP_001189105.1	Gene:	CG6833 / 39559	FlyBaseID:	FBgn0036405	Length:	290	Species:	Drosophila melanogaster
Sequence 2:	NP_001034073.1	Gene:	CG12877 / 43333	FlyBaseID:	FBgn0039544	Length:	991	Species:	Drosophila melanogaster

Alignment Length:	183	Identity:	60/183 - (32%)
Similarity:	83/183 - (45%)	Gaps:	42/183 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   117 ILAMDCEMVGVGHNTRDDMLARVSIVNRMGHVLLDKYVKPRKEVTDYRTSVSGIRPQDIAN-GED 180
            |.|:||||....|...   |.||::|:..|..:.|..|||..::.||.|:.|||....::| ...
  Fly   833 IYALDCEMCYTTHGIE---LTRVTVVDINGRSVYDALVKPDNQIVDYNTTYSGITEAMLSNETRT 894

  Fly   181 FAAVQNEVMKLIHGR-ILVGHGLRNDLAVLGIRHPFHD-IRDTS----H---------YKPLCKL 230
            ...||..:|.:.|.: :||||.|.:||..|.:   .|| :.|||    |         .|.||
  Fly   895 IRDVQAVLMSMFHAKTVLVGHSLESDLKALKL---IHDVVVDTSVLFPHKMGPPKKRALKTLC-- 954

  Fly   231 ISNTHTPSLKRLTKAVLGQEIQTGEHNSVEDARAAMGIYNRVAVDWEKYLEKK 283
            |.|     |||:.     ||.:.| |:|.|||...:.:.       :.||..|
  Fly   955 IEN-----LKRII-----QESEAG-HDSAEDAEVCIQLI-------KYYLRNK 989

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6833	NP_001189105.1	DnaQ	100..>283	CDD:223916	59/181 (33%)
CG6833	NP_001189105.1	REX4_like	118..270	CDD:99847	56/167 (34%)
CG12877	NP_001034073.1	CDC45	129..>199	CDD:280821
		EloA-BP1	572..736	CDD:292495
		REX1_like	834..983	CDD:99848	56/174 (32%)
		DnaQ	847..>991	CDD:223916	53/169 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45460581
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0847
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR12801
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840