DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6833 and Pan2

DIOPT Version :9

Sequence 1:	NP_001189105.1	Gene:	CG6833 / 39559	FlyBaseID:	FBgn0036405	Length:	290	Species:	Drosophila melanogaster
Sequence 2:	NP_001382635.1	Gene:	Pan2 / 408200	RGDID:	1303301	Length:	1207	Species:	Rattus norvegicus

Alignment Length:	232	Identity:	62/232 - (26%)
Similarity:	100/232 - (43%)	Gaps:	59/232 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    97 SAPLSKSARMRMKKKAHRNRILAMDCEMVGVGH----------------NTRDD----------- 134
            |..|::::..|.::|.|...|..|..||..||.                ..|.|
  Rat   946 SVLLAEASLARKQRKTHTTFIPLMLNEMPQVGDLVGLDAEFVTLNEEEAELRSDGTKSTIKPSQM 1010

  Fly   135 MLARVSIVNRMGH----VLLDKYVKPRKEVTDYRTSVSGIRPQDI---ANGEDFAAVQNEVMKLI 192
            .:||::.|...|.    ..:|.|:..:::|.||.|..|||:|.|:   .:.:....:::..:||
  Rat  1011 SVARITCVRGQGPNEGIPFIDDYISTQEQVVDYLTQYSGIKPGDLDAKISSKHLTTLKSTYLKL- 1074

  Fly   193 HGRIL-------VGHGLRNDLAVLGIRHPFHDIRDTSH--YKPLCKLISNTHTPSLKRLTKAVLG 248
              |.|       |||||:.|..|:.:..|...:.||.:  :.|..::|      ||:.|....|.
  Rat  1075 --RFLIDIGVKFVGHGLQKDFRVINLMVPKDQVLDTVYLFHMPRKRMI------SLRFLAWYFLD 1131

  Fly   249 QEIQTGEHNSVEDARAAMGIYNRVAVDWEKYLEKKRH 285
            .:||...|:|:||||.|:.:|       .||||..::
  Rat  1132 LKIQGETHDSIEDARTALQLY-------RKYLELSKN 1161

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6833	NP_001189105.1	DnaQ	100..>283	CDD:223916	61/225 (27%)
CG6833	NP_001189105.1	REX4_like	118..270	CDD:99847	51/194 (26%)
Pan2	NP_001382635.1	WD 1. /evidence=ECO:0000255\|HAMAP-Rule:MF_03182	153..193
		WD 2. /evidence=ECO:0000255\|HAMAP-Rule:MF_03182	195..231
		WD 3. /evidence=ECO:0000255\|HAMAP-Rule:MF_03182	244..280
		WD 4. /evidence=ECO:0000255\|HAMAP-Rule:MF_03182	328..367
		Linker. /evidence=ECO:0000255\|HAMAP-Rule:MF_03182	368..484
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0847
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810