DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6833 and Aen

DIOPT Version :9

Sequence 1:	NP_001189105.1	Gene:	CG6833 / 39559	FlyBaseID:	FBgn0036405	Length:	290	Species:	Drosophila melanogaster
Sequence 2:	NP_001101957.1	Gene:	Aen / 361594	RGDID:	1305051	Length:	332	Species:	Rattus norvegicus

Alignment Length:	276	Identity:	98/276 - (35%)
Similarity:	135/276 - (48%)	Gaps:	27/276 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 TTDSTKNVVSPQHNQRKLQ-----ASMERLQVQQVNTSRRAAG-----SNWMAAAGGGAAAAAGS 87
            |:..||:|...:|.:|..|     |....||.|:..:.....|     |.....||   ..|:|:
  Rat    12 TSLKTKDVARRRHKRRSRQHQRFMARKALLQEQESLSMVPGPGLCPLPSPTQTPAG---TEASGN 73

  Fly    88 ENQDAKATESAP--LSKSARMRMKKKAHRNRILAMDCEMVGVGHNTRDDMLARVSIVNRMGHVLL 150
            ..|..||...:.  .||....|....:..::.:|:||||||.|...|...|||.|:|:..|.||.
  Rat    74 RKQRTKARSGSKGLCSKRPVPREAPSSGPSKYVAIDCEMVGTGPQGRVSELARCSVVSYSGDVLY 138

  Fly   151 DKYVKPRKEVTDYRTSVSGIRPQDIANGEDFAAVQNEVMKLIHGRILVGHGLRNDLAVLGIRHPF 215
            |||::|...:.||||..|||..|.:.....|...|.|::||:.|:::|||.|.||...|...||.
  Rat   139 DKYIRPEMPIVDYRTRWSGITRQHMHKAIPFQVAQKEILKLLKGKVVVGHALHNDFQALKYVHPG 203

  Fly   216 HDIRDTSHYKPLCKLISNTHT-----PSLKRLTKAVLGQEIQTGE--HNSVEDARAAMGIYNRVA 273
            ..||||: |.|  .|:|...:     .|||.|...:|.::||.|.  |:|||||..||.:|..|.
  Rat   204 SQIRDTT-YVP--NLLSQPSSLTRARVSLKDLALNLLHKKIQVGHHGHSSVEDAMTAMELYQLVE 265

  Fly   274 VDWEKYLEK--KRHQQ 287
            |.||:.:..  |.|.:
  Rat   266 VQWEQQVASTAKAHPE 281

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6833	NP_001189105.1	DnaQ	100..>283	CDD:223916	76/191 (40%)
CG6833	NP_001189105.1	REX4_like	118..270	CDD:99847	68/158 (43%)
Aen	NP_001101957.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..102		23/92 (25%)
		Nucleolar localization signal. /evidence=ECO:0000250\|UniProtKB:Q8WTP8	21..29		2/7 (29%)
		DnaQ	102..>263	CDD:223916	69/163 (42%)
		DnaQ_like_exo	106..262	CDD:299142	68/158 (43%)
		Nuclear localization signal. /evidence=ECO:0000250\|UniProtKB:Q8WTP8	160..183		6/22 (27%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	272..332		2/10 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0847
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	132	1.000	Inparanoid score	I4521
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1562214at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12801
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.970