DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6833 and PAN2

DIOPT Version :9

Sequence 1:	NP_001189105.1	Gene:	CG6833 / 39559	FlyBaseID:	FBgn0036405	Length:	290	Species:	Drosophila melanogaster
Sequence 2:	NP_610427.2	Gene:	PAN2 / 35893	FlyBaseID:	FBgn0033352	Length:	1241	Species:	Drosophila melanogaster

Alignment Length:	297	Identity:	77/297 - (25%)
Similarity:	121/297 - (40%)	Gaps:	78/297 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 DSSRSGSANNKNTTDS--------------------TKNVVSPQHNQRKLQASMERLQVQQVNTS 65
            |.|.|.|..:...|:|                    .:.:|||........|:::.||
  Fly   968 DDSESASTTSSTVTESEETIPSESSSGSPTNLSNPFLEEIVSPMLGNLSADATLQPLQ------- 1025

  Fly    66 RRAAGSNWMAAAGGGAAAAAGSENQDAKATESAPLSKSARMRMKKKAHRNRILAMDCEMVGVGHN 130
                 |:.|..:|...|..|.....:.:..|..|..|:|.::             .|.|
  Fly  1026 -----SDEMPQSGDLVAMDAEFVTLNPEENEIRPDGKTATIK-------------PCHM------ 1066

  Fly   131 TRDDMLARVSIVNRMGHV----LLDKYVKPRKEVTDYRTSVSGIRPQDI-AN--GEDFAAVQNEV 188
                .:||:|.:...|..    .:|.|:..:::|.||.|..|||:|.|: ||  .:...|::...
  Fly  1067 ----SVARISCIRGQGPAEGVPFMDDYISTQEKVVDYLTQFSGIKPGDLDANFSKKRLTALKYSY 1127

  Fly   189 MKLIH----GRILVGHGLRNDLAVLGIRHPFHDIRDTSH--YKPLCKLISNTHTPSLKRLTKAVL 247
            .||.:    |.|.|||||:||..|:.|..|...|.||.|  :.|..:::      ||:.|....|
  Fly  1128 QKLKYLVDVGVIFVGHGLKNDFRVINIYVPSEQIIDTVHLFHMPHHRMV------SLRFLAWHFL 1186

  Fly   248 GQEIQTGEHNSVEDARAAMGIYNRVAVDWEKYLEKKR 284
            |.:||:..|:|:||||..:.:|..    :.|..|:|:
  Fly  1187 GTKIQSETHDSIEDARTTLQLYKH----YLKLQEEKK 1219

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6833	NP_001189105.1	DnaQ	100..>283	CDD:223916	57/195 (29%)
CG6833	NP_001189105.1	REX4_like	118..270	CDD:99847	52/164 (32%)
PAN2	NP_610427.2	WD40	63..>270	CDD:330360
		WD40 repeat	148..183	CDD:293791
		WD40 repeat	187..221	CDD:293791
		WD40 repeat	227..273	CDD:293791
		WD40 repeat	278..314	CDD:293791
		UCH_1	505..940	CDD:315986
		zf-CCCH_2	799..816	CDD:317060
		PAN2_exo	1036..1209	CDD:99846	58/201 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0847
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810