DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6833 and Isg20l2

DIOPT Version :9

Sequence 1:	NP_001189105.1	Gene:	CG6833 / 39559	FlyBaseID:	FBgn0036405	Length:	290	Species:	Drosophila melanogaster
Sequence 2:	NP_808331.1	Gene:	Isg20l2 / 229504	MGIID:	2140076	Length:	368	Species:	Mus musculus

Alignment Length:	301	Identity:	96/301 - (31%)
Similarity:	154/301 - (51%)	Gaps:	40/301 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 PRQKQFDMNRSRANNLDSSRSGSANNKNT---------TDSTKNVVSPQHNQRKLQASMERLQVQ 60
            |::|:     :.|:..||.:|   .:|..         :..|.:|||......:.|:::.:.:..
Mouse    76 PKKKE-----AAASKRDSEQS---KDKKAPLSWLTPAPSKKTASVVSKIDLLGEFQSALPKTKST 132

  Fly    61 QVNTSRRAAGSNWMAAAGGGAAAAAGSENQDAKATESAPLSKSA-----RMRMKKKAHR------ 114
            |...|::.:....:|......|     :::| |.::..||.|:|     :.|.:.|...
Mouse   133 QKKGSKKKSLKKKIATENSTQA-----QSKD-KGSKKKPLKKNAVPNSTQARSEDKCPTVPQNLP 191

  Fly   115 NRILAMDCEMVGVGHNTRDDMLARVSIVNRMGHVLLDKYVKPRKEVTDYRTSVSGIRPQDIANGE 179
            .:::|:||||||.|...|...|||.||||..|.||.|:||.|...:.:|||..||||...:.|..
Mouse   192 GKMVAIDCEMVGTGPKGRVSSLARCSIVNYNGDVLYDEYVLPPCYIVNYRTRWSGIRKCHMVNAT 256

  Fly   180 DFAAVQNEVMKLIHGRILVGHGLRNDLAVLGIRHPFHDIRDTSHYKPLCKLISN---THTPSLKR 241
            .|...:::::|::.|::::||.:.||...|...||....||||.. ||....::   ..|.|||.
Mouse   257 PFKTARSQILKILSGKVVIGHAIHNDYKALQYFHPKSLTRDTSRI-PLLNRKADCPENVTLSLKH 320

  Fly   242 LTKAVLGQEIQTGE--HNSVEDARAAMGIYNRVAVDWEKYL 280
            |||.:|.::||.|.  |:|||||:|.|.:|..|.|:||::|
Mouse   321 LTKKLLSRDIQVGNTGHSSVEDAQATMELYKLVEVEWEQHL 361

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6833	NP_001189105.1	DnaQ	100..>283	CDD:223916	77/197 (39%)
CG6833	NP_001189105.1	REX4_like	118..270	CDD:99847	66/156 (42%)
Isg20l2	NP_808331.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	33..107		7/38 (18%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	127..187		12/65 (18%)
		ISG20	195..351	CDD:99852	66/156 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0847
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1562214at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12801
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.920