DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6833 and Rexo4

DIOPT Version :9

Sequence 1:	NP_001189105.1	Gene:	CG6833 / 39559	FlyBaseID:	FBgn0036405	Length:	290	Species:	Drosophila melanogaster
Sequence 2:	NP_997117.2	Gene:	Rexo4 / 227656	MGIID:	2684957	Length:	432	Species:	Mus musculus

Alignment Length:	313	Identity:	111/313 - (35%)
Similarity:	158/313 - (50%)	Gaps:	52/313 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 NRSRANNLDSSRSGSANNKNTTDSTKNVVSPQHNQRKL------------QASMERLQVQQVNTS 65
            ||.:|:  |.|: |.........||:..|:.....||:            :...::.....:::.
Mouse   118 NRKKAS--DKSK-GDKQRTEKAKSTRGSVTSAPTDRKILVPPTDTSGTEQKKGAKKRTYSDISSH 179

  Fly    66 RRAAGSNWMAAAGGGAAAAAGSENQ-------------------DAKATESAPLSKSARMRMKKK 111
            :.|....|.      |..||...||                   ||...|:|.|.:. |:..||:
Mouse   180 QGALKPKWK------ATEAAVILNQPTPTEEDIWFDDVDPDDIEDAIGPEAAMLVRK-RLGQKKR 237

  Fly   112 ----------AHRNRILAMDCEMVGVGHNTRDDMLARVSIVNRMGHVLLDKYVKPRKEVTDYRTS 166
                      ....:.||:||||||||....:.:.|||||||:.|..:.||||||.:.||||||:
Mouse   238 TISLEKEQAFGGLTKALALDCEMVGVGPKGEESIAARVSIVNQYGKCVYDKYVKPTEPVTDYRTA 302

  Fly   167 VSGIRPQDIANGEDFAAVQNEVMKLIHGRILVGHGLRNDLAVLGIRHPFHDIRDTSHYKPLCKLI 231
            ||||||:::..||:|..|:.||.:::.|||||||.|.|||.||.:.||...||||..:||....:
Mouse   303 VSGIRPENLKQGEEFEVVKKEVAEMLKGRILVGHALHNDLKVLFLDHPKKKIRDTQKFKPFRSRV 367

  Fly   232 SNTHTPSLKRLTKAVLGQEIQTGEHNSVEDARAAMGIYNRVAVDWEKYLEKKR 284
            .:.. ||||||::.:||..:|..||.|::||:|||.:|..|..:||.....:|
Mouse   368 KSGR-PSLKRLSEKILGIRVQQAEHCSIQDAQAAMRLYVMVKREWESSTANRR 419

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6833	NP_001189105.1	DnaQ	100..>283	CDD:223916	88/192 (46%)
CG6833	NP_001189105.1	REX4_like	118..270	CDD:99847	80/151 (53%)
Rexo4	NP_997117.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	42..177		11/61 (18%)
		DnaQ	251..>414	CDD:223916	84/163 (52%)
		REX4_like	254..404	CDD:99847	80/150 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167836995
Domainoid	1	1.000	161	1.000	Domainoid score	I4018
eggNOG	1	0.900	-	-		E1_COG0847
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S1595
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004095
OrthoInspector	1	1.000	-	-		oto94233
orthoMCL	1	0.900	-	-		OOG6_102721
Panther	1	1.100	-	-	LDO	PTHR12801
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1084
SonicParanoid	1	1.000	-	-		X2840
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.680