DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6833 and panl-2

DIOPT Version :9

Sequence 1:	NP_001189105.1	Gene:	CG6833 / 39559	FlyBaseID:	FBgn0036405	Length:	290	Species:	Drosophila melanogaster
Sequence 2:	NP_498519.1	Gene:	panl-2 / 175974	WormBaseID:	WBGene00017951	Length:	1131	Species:	Caenorhabditis elegans

Alignment Length:	305	Identity:	77/305 - (25%)
Similarity:	115/305 - (37%)	Gaps:	61/305 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 LDSSRSGSANNKNTTDSTKNVV----SPQHNQRKLQASMERLQVQQVNT----SRRAAGSNWMAA 76
            ||:......|.:|..:.|..|.    ||     .:.:|...:..|.|:.    ..|.....|...
Worm   797 LDAMIHAVGNGENDVNWTHPVTLLRESP-----VISSSWTLINEQLVSRLHDHEARHIDGRWKLP 856

  Fly    77 AGGGAAAAAGSENQDAKATE---------------SAPLSKSARMRMKKKAHRNRILAMDCEMVG 126
                |..|...:|.|.|.:|               |..::..|...:::......::.:|.|.:.
Worm   857 ----ALLAYKKKNFDVKTSEDIISNDLFLAEENLASNGMTSLAVQSLEELPKEKELVGLDAEFIK 917

  Fly   127 V--------GHNTRDDMLARVSIVNRMG-HVLLDKYVK--PRKEVTDYRTSVSGIRPQDI--ANG 178
            :        |...:...:.|.|.|:..| .::.|.:||  ...||.||.|..|||...|:  ...
Worm   918 IKTDLLEFDGKTVQMRAVGRASCVDSTGERIIFDDHVKLTDDVEVVDYLTKFSGIVKADLCPTTS 982

  Fly   179 EDFAAVQNEVMKLIH-----GRILVGHGLRNDLAVLGIRHPFHDIRDTSHYKPLCKLISNTHTPS 238
            |.:......::..:|     |...|||.|.||..||.:......|.||   ..|.:| ......|
Worm   983 EKYLTTHKRLLLRMHVLIQRGVTFVGHALHNDFTVLNVHVAESQIIDT---VTLMRL-GTQRMLS 1043

  Fly   239 LKRLTKAVLGQEIQTGEHNSVEDARAAMGIYNRVAVDWEKYLEKK 283
            |:.|.|.:||:.||...|:||.|||.|:.:|       .||||.|
Worm  1044 LQFLVKEILGETIQMEAHDSVVDARYALKLY-------RKYLEIK 1081

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6833	NP_001189105.1	DnaQ	100..>283	CDD:223916	56/200 (28%)
CG6833	NP_001189105.1	REX4_like	118..270	CDD:99847	50/169 (30%)
panl-2	NP_498519.1	WD40	<17..322	CDD:225201
		WD40	28..324	CDD:295369
		Peptidase_C19	493..>613	CDD:271592
		PAN2_exo	909..1075	CDD:99846	51/176 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0847
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810