DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6833 and Pan2

DIOPT Version :9

Sequence 1:	NP_001189105.1	Gene:	CG6833 / 39559	FlyBaseID:	FBgn0036405	Length:	290	Species:	Drosophila melanogaster
Sequence 2:	XP_006513048.1	Gene:	Pan2 / 103135	MGIID:	1918984	Length:	1205	Species:	Mus musculus

Alignment Length:	232	Identity:	62/232 - (26%)
Similarity:	100/232 - (43%)	Gaps:	59/232 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    97 SAPLSKSARMRMKKKAHRNRILAMDCEMVGVGH----------------NTRDD----------- 134
            |..|::::..|.::|.|...|..|..||..||.                ..|.|
Mouse   945 SVLLAEASLARKQRKTHTTFIPLMLNEMPQVGDLVGLDAEFVTLNEEEAELRSDGTKSTIKPSQM 1009

  Fly   135 MLARVSIVNRMGH----VLLDKYVKPRKEVTDYRTSVSGIRPQDI---ANGEDFAAVQNEVMKLI 192
            .:||::.|...|.    ..:|.|:..:::|.||.|..|||:|.|:   .:.:....:::..:||
Mouse  1010 SVARITCVRGQGPNEGIPFIDDYISTQEQVVDYLTQYSGIKPGDLDAKISSKHLTTLKSTYLKL- 1073

  Fly   193 HGRIL-------VGHGLRNDLAVLGIRHPFHDIRDTSH--YKPLCKLISNTHTPSLKRLTKAVLG 248
              |.|       |||||:.|..|:.:..|...:.||.:  :.|..::|      ||:.|....|.
Mouse  1074 --RFLIDIGVKFVGHGLQKDFRVINLMVPKDQVLDTVYLFHMPRKRMI------SLRFLAWYFLD 1130

  Fly   249 QEIQTGEHNSVEDARAAMGIYNRVAVDWEKYLEKKRH 285
            .:||...|:|:||||.|:.:|       .||||..::
Mouse  1131 LKIQGETHDSIEDARTALQLY-------RKYLELSKN 1160

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6833	NP_001189105.1	DnaQ	100..>283	CDD:223916	61/225 (27%)
CG6833	NP_001189105.1	REX4_like	118..270	CDD:99847	51/194 (26%)
Pan2	XP_006513048.1	WD40	75..357	CDD:421866
		UCH_1	516..902	CDD:404327
		PAN2_exo	979..1152	CDD:99846	47/188 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0847
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810