Protein Alignment Neurl4 and neurl1aa

DIOPT Version :9

• Sequence 1: NP_648688.2
• Gene: Neurl4 / 39558
• FlyBaseID: FBgn0283503
• Length: 1780
• Species: Drosophila melanogaster
• Sequence 2: XP_021330967.1
• Gene: neurl1aa / 561943
• ZFINID: ZDB-GENE-090311-3
• Length: 572
• Species: Danio rerio
• Alignment Length: 528
• Identity: 113/528 - (21%)
• Similarity: 187/528 - (35%)
• Gaps: 167/528 - (31%)

  Fly    12 RCG---RSIRLYNNNR--------MAQRSMR---DFSHALVFSAEPLEDDVLFEVV---IEKKNT 59
            :||   .|..|::.|.        :||||::   .|.:|:.||..|:   .|:|.|   |.||..
Zfish    51 QCGGVLMSPLLFHPNAKGSQIVMDLAQRSVKRQASFCNAITFSNRPI---ALYEQVRLKITKKQC 112

  Fly    60 YWGGSIEIGVTAE-----SPDDLELVACATAM-RNGTWVMSGIDVRKDGRRLFEFYGTDLETLNE 118
            .|.|::.:|.|::     :||.|...||...: ::|.|..:..:...:...|..|:      :::
Zfish   113 CWSGALRLGFTSKDPSRINPDSLPKYACPDLVSQSGFWAKALPEEFANEGNLISFW------VDK 171

  Fly   119 NDRVGVMRTSGNDLVFYVNGESQGVAAKNMPKPLWALVDLYG--RCVQ----------------- 164
            ..||.......:.::|:     .||   ...:|||||:|:||  |.||
Zfish   172 KGRVFYRINDSSPMLFF-----SGV---RTTEPLWALIDVYGLTRGVQLLESEVVPPDLLRPRSF 228

  Fly   165 -------------------VSLC----PRDGSGSGELLDSPLQQPLQQVVQNLDVAMNVNIVVDS 206
                               ||||    |:|.|.. .|..:|:..|:.|...|...:..:...::.
Zfish   229 TTVRGSTSLRREADTSRLSVSLCDLNLPQDDSRL-RLPPAPVTCPIPQNSMNSQQSSLLPHTLEC 292

  Fly   207 DAWMQGNGSVSGADDRLCFHTRCGSLVKLSPNFRSAERRRPLDEFNNGVVMTHRPLRDNELFEIR 271
            |               :.||...|:.:|:......|......:|  ..:|.|.||||..|...|:
Zfish   293 D---------------IRFHQLRGAHIKILNEQTVARSEHNREE--RTLVFTDRPLRIGETIFIK 340

  Fly   272 IDKLVDKWSGSIEVGVTTHNPAVL------HFPATMTNMRSGTIMMSGCGILTNGKGTRRQYGEF 330
            :.|......||:..|||:.:||||      :.|..:.:.:.   ..:.|.:.|
Zfish   341 VIKSSPARFGSLSYGVTSCDPAVLRPSDLPYNPEALVDRKE---FWAVCRVPT------------ 390

  Fly   331 NLDELREGDRVGMMRKANGNL---HNYINGQDQGVAATRAPSTLWGVIDLYGMTIKVTIVDR--- 389
               .|:..|.:|.:....|.:   ||..|...|.......|  ||....|:|...::.|:..
Zfish   391 ---ALQSADILGFLVTQEGEVILSHNGTNVGMQVCVDNSRP--LWMFFGLHGAVTQLRILGSTFL 450

  Fly   390 -DEREQQNLVTRRNNIVAGMTACSSGAGAQHTQHQQHSGTPTLSLL-----SPESEMNAAGAAGG 448
             |.|:..:                             .|:|:.|..     |||..::..|.:..
Zfish   451 GDARDPSS-----------------------------PGSPSASPSGLCGGSPEPSLHERGCSAA 486

  Fly   449 LSETISST 456
            ...:...|
Zfish   487 FCSSTEGT 494

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Neurl4	NP_648688.2	NEUZ	5..126	CDD:128856	35/136 (26%)
		SPRY_NHR_like	8..168	CDD:293945	51/216 (24%)
		NEUZ	221..345	CDD:128856	30/129 (23%)
		SPRY_NHR_like	225..387	CDD:293945	40/170 (24%)
		NEUZ	464..587	CDD:128856
		SPRY_NHR_like	467..629	CDD:293945
		NEUZ	653..777	CDD:128856
		SPRY_NHR_like	656..818	CDD:293945
		SPRY_NHR_like	854..1016	CDD:293945
		SPRY_NHR_like	1063..1220	CDD:293945
neurl1aa	XP_021330967.1	NEUZ	59..180	CDD:128856	32/129 (25%)
		Neuralized	296..446	CDD:311244	41/171 (24%)
		mRING-HC-C3HC5_NEU1A	517..560	CDD:319699
		modified RING-HC finger (C3HC5-type)	519..558	CDD:319699

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910