DRSC/TRiP Functional Genomics Resources

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Protein Alignment Neurl4 and Neurl2

DIOPT Version :9

Sequence 1:NP_648688.2 Gene:Neurl4 / 39558 FlyBaseID:FBgn0283503 Length:1780 Species:Drosophila melanogaster
Sequence 2:NP_001076443.1 Gene:Neurl2 / 415115 MGIID:3043305 Length:285 Species:Mus musculus


Alignment Length:263 Identity:58/263 - (22%)
Similarity:97/263 - (36%) Gaps:76/263 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly   654 PLRFHSIHGANAGISNSGLTASRPNSLAEFNDAIVFSNRPLRQRELFEVELETMVRHWSGNIEIG 718
            |.|||.:||||..:..||..|:|..|.|.   .:.||..||...::|.||:|.....|.|::.:|
Mouse    23 PTRFHQVHGANIRMDPSGTRATRVESFAH---GVCFSREPLAPGQVFLVEIEEKELGWCGHLRLG 84

  Fly   719 VTGTRPEDIQLAPNATDLEASDTIILCGPMIF-----HNR------------------------- 753
            :|...|..:...|   :....|.:.|....:|     |||                         
Mouse    85 LTALDPASLAAVP---EFSLPDLVSLGHSWVFAITRHHNRVPREGQPEAEAAVPSGPQALLVEPY 146

  Fly   754 ------KTIRTNI---------------LLDLDTLGPS---TRVGVM----RNGDF-IHFFVDGM 789
                  :..|..:               |.:.:.|.|:   :|:||:    .:|.. :|..::|.
Mouse   147 LRIEQFRIPRDRLVGRSRPGLYSHLLDQLYEQNVLPPTARRSRLGVLFCPREDGTADMHIIINGE 211

  Fly   790 DQGPACE--CHAPNIWAIIDLYGQCAQVSLTQTQLDIRAPYATSENSQSCQAT---SVIQHPAME 849
            |.||:..  ..|..::|::|::.....|.|.|.:      |........|:..   .|:...|::
Mouse   212 DMGPSARGLPAAQPLYAVVDVFASTKSVRLVQLE------YGLPSLQTLCRLVIQKRVVHRLAID 270

  Fly   850 TKH 852
            ..|
Mouse   271 VLH 273

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Neurl4NP_648688.2 NEUZ 5..126 CDD:128856
SPRY_NHR_like 8..168 CDD:293945
NEUZ 221..345 CDD:128856
SPRY_NHR_like 225..387 CDD:293945
NEUZ 464..587 CDD:128856
SPRY_NHR_like 467..629 CDD:293945
NEUZ 653..777 CDD:128856 41/180 (23%)
SPRY_NHR_like 656..818 CDD:293945 50/222 (23%)
SPRY_NHR_like 854..1016 CDD:293945
SPRY_NHR_like 1063..1220 CDD:293945
Neurl2NP_001076443.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..28 3/4 (75%)
SPRY_NHR_like 25..242 CDD:293945 50/222 (23%)
SOCS_box 249..285 CDD:198037 4/25 (16%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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