Protein Alignment Hsc70Cb and SSA4

DIOPT Version :9

• Sequence 1: NP_001189103.1
• Gene: Hsc70Cb / 39557
• FlyBaseID: FBgn0026418
• Length: 836
• Species: Drosophila melanogaster
• Sequence 2: NP_011029.3
• Gene: SSA4 / 856840
• SGDID: S000000905
• Length: 642
• Species: Saccharomyces cerevisiae
• Alignment Length: 695
• Identity: 205/695 - (29%)
• Similarity: 333/695 - (47%)
• Gaps: 111/695 - (15%)

  Fly     4 IGIDFGNESCYVAAARSGGIETLANDYSLRATPSFVAFDGKKRIIGVAAKNQQVTNMKNTVGGFK 68
            :|||.|.....||...:..:|.:|||...|.|||:|||...:|:||.|||||...|..|||...|
Yeast     5 VGIDLGTTYSCVAHFANDRVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQAAMNPHNTVFDAK 69

  Fly    69 RLLGRKFNDPHVQHELTSIPARVEARGDGSIGIKVNYLGEDQHFGPEQLTAMLFTKLKETSAAAM 133
            ||:||||:||.|.::....|.:|..:| |...::|.|.||.:.|.||::::|:.||:|||:...:
Yeast    70 RLIGRKFDDPEVTNDAKHYPFKVIDKG-GKPVVQVEYKGETKTFTPEEISSMILTKMKETAENFL 133

  Fly   134 QTQVNDCVIACPVFFTNAERKALLDAAQIAGLNVLRLMNETTATALAYGFYKNDLFEDKPRNVIF 198
            .|:|.|.|:..|.:|.:::|:|..||..||||||||::||.||.|:|||..|.   ..|..||:.
Yeast   134 GTEVKDAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKK---SQKEHNVLI 195

  Fly   199 VDFGHSSLQASACAFTKGKLKMLASTWD-QIGGRDIDLALGDYFAKEFQERYKINAKTNARANLR 262
            .|.|..:...|..:..:|..::.|:..| .:||.|.|..|.::.|:||:.:.|.:..||.|:..|
Yeast   196 FDLGGGTFDVSLLSIDEGVFEVKATAGDTHLGGEDFDSRLVNFLAEEFKRKNKKDLTTNQRSLRR 260

  Fly   263 LLTEIEKLKKQMSANSTKLPLNIECFLDDIDVSSSMQRSQMEELCAPVLQRVEQTFKRLLAESKL 327
            |.|..|:.|:.:| :|.:..:.|:...:.||..:|:.|::.|||||.:.:...:..:::||:|||
Yeast   261 LRTAAERAKRTLS-SSAQTSIEIDSLFEGIDFYTSITRARFEELCADLFRSTLEPVEKVLADSKL 324

  Fly   328 QLDDIHSVEIVGGSSRIPSVKQLIEQVFN-KPASTTLNQDEAVSRGAALQCAIMSP--------- 382
            ....|..:.:||||:|||.|::|:...|| |..:.::|.||||:.|||:|.||::.
Yeast   325 DKSQIDEIVLVGGSTRIPKVQKLVSDFFNGKEPNRSINPDEAVAYGAAVQAAILTGDQSSTTQDL 389

  Fly   383 ---AVRVREFGVTDIQNYAVKVLWDSEGSAAP-GEIEIFPQYHASPFSRLLTINRKGPFNVSIVY 443
               .|.....|:........|::  ...|..| .:.|:|..|         ..|:.|.. :.:..
Yeast   390 LLLDVAPLSLGIETAGGIMTKLI--PRNSTIPTKKSEVFSTY---------ADNQPGVL-IQVFE 442

  Fly   444 GQQVPYPDQT-IGVWKVKDVKPTERGEGQDVKLKVRINNNGIVLISSATLVEKKEAEEAAAAAEQ 507
            |::....|.. :|.:::..:.|..||..| :::...|:.|||:.:|:   |||
Yeast   443 GERTRTKDNNLLGKFELSGIPPAPRGVPQ-IEVTFDIDANGILNVSA---VEK------------ 491

  Fly   508 AASEEKPGDQTNNTGEPADGQQEAYCENEDDNNTSTASSPGGQGWAQRVKGWFGSGADKKKKASK 572
                        .||:               :|..|.::..|:
Yeast   492 ------------GTGK---------------SNKITITNDKGR---------------------- 507

  Fly   573 ATELPLECTTHGFSPVDLSNYTQQESKMIGNDQKETERIDAKNALEEFVYDMRNKLQGGPFERYV 637
                        .|..|:.....:..|....|::|.:|:.|||.||.:.:.::|.:....|:..|
Yeast   508 ------------LSKEDIDKMVAEAEKFKAEDEQEAQRVQAKNQLESYAFTLKNSVSENNFKEKV 560

  Fly   638 VEAEREKIVSQLNDLENWLYEDGEDCERDIYTSRLQALHQKTDPI 682
            .|.:..|:.:...|..||| :..:....:.|..|.:.|....:||
Yeast   561 GEEDARKLEAAAQDAINWL-DASQAASTEEYKERQKELEGVANPI 604

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70Cb	NP_001189103.1	HSPA4_like_NDB	2..381	CDD:212670	150/378 (40%)
		HSP70	3..682	CDD:278441	203/693 (29%)
SSA4	NP_011029.3	PTZ00009	4..642	CDD:240227	205/695 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810