Protein Alignment Hsp110 and SSZ1

DIOPT Version :10

• Sequence 1: NP_001189103.1
• Gene: Hsp110 / 39557
• FlyBaseID: FBgn0026418
• Length: 836
• Species: Drosophila melanogaster
• Sequence 2: NP_011931.2
• Gene: SSZ1 / 856461
• SGDID: S000001106
• Length: 538
• Species: Saccharomyces cerevisiae
• Alignment Length: 532
• Identity: 136/532 - (25%)
• Similarity: 239/532 - (44%)
• Gaps: 71/532 - (13%)

  Fly     3 VIGIDFGNESCYVAAAR-SGGIETLANDYSLRATPSFVAFDGKKRIIGVAAKNQQVTNMKNTVGG 66
            ||||.|||.|..:|... ...::.:||....||.||.:::.|:....|..|..|.:.|.|||:..
Yeast     5 VIGITFGNTSSSIAYINPKNDVDVIANPDGERAIPSALSYVGEDEYHGGQALQQLIRNPKNTIIN 69

  Fly    67 FKRLLGRKFNDPHVQHELTSIPARVEARGDGSIGIKVNY-LGEDQHFGPEQLTAMLFTKLKETSA 130
            |:..:|..|:...|.......|| ||.  ||.:|..::. .|:::....:::.:....:||..:.
Yeast    70 FRDFIGLPFDKCDVSKCANGAPA-VEV--DGKVGFVISRGEGKEEKLTVDEVVSRHLNRLKLAAE 131

  Fly   131 AAMQTQVNDCVIACPVFFTNAERKALLDAAQIAGLNVLRLMNETTATALAYGFYKNDLFE-DKPR 194
            ..:.:.|.:.|:..|..|:..::.||..:|...||.:::.:||.:|..||:.    :.|. :|..
Yeast   132 DYIGSAVKEAVLTVPTNFSEEQKTALKASAAKIGLQIVQFINEPSAALLAHA----EQFPFEKDV 192

  Fly   195 NVIFVDFGHSSLQASACAFTKGKLKMLASTWD-QIGGRDIDLALGDYFAKEFQERYKINAKTNAR 258
            ||:..|||.....|:..|...|...:||:..| .:||.::|..|.:|||.|||::|:.|.:.|||
Yeast   193 NVVVADFGGIRSDAAVIAVRNGIFTILATAHDLSLGGDNLDTELVEYFASEFQKKYQANPRKNAR 257

  Fly   259 ANLRLLTEIEKLKKQMSANSTKLPLNIECFLDDIDVSSSMQRSQMEELCAPVLQRVEQTFKRLLA 323
            :..:|.......||.:| |:|...::|:...|..|..:|:.|.:.|.:...|..:.......::|
Yeast   258 SLAKLKANSSITKKTLS-NATSATISIDSLADGFDYHASINRMRYELVANKVFAQFSSFVDSVIA 321

  Fly   324 ESKLQLDDIHSVEIVGGSSRIPSVKQLIEQVF----------NKPASTTLNQDEAVSRGAALQCA 378
            :::|...||.:|.:.||.|..|.:...:|...          ||.||.  |.:|..:.|||||..
Yeast   322 KAELDPLDIDAVLLTGGVSFTPKLTTNLEYTLPESVEILGPQNKNASN--NPNELAASGAALQAR 384

  Fly   379 IMSPAVRVREFGVTDIQNYAVKVLWDSEGSAAP-GEIEIFPQYH-------ASPFSRLLTINR-K 434
            ::|      ::...::......|:.::.....| |.|....::|       :.|..:.||:.: |
Yeast   385 LIS------DYDADELAEALQPVIVNTPHLKKPIGLIGAKGEFHPVLLAETSFPVQKKLTLKQAK 443

  Fly   435 GPFNVSIVYGQQ-------VPYPDQTIGVWKVKDVKPTERGEGQD-----------------VKL 475
            |.|.:.:..|..       .|.|       |.::.:..:..|..|                 ::|
Yeast   444 GDFLIGVYEGDHHIEEKTLEPIP-------KEENAEEDDESEWSDDEPEVVREKLYTLGTKLMEL 501

  Fly   476 KVRINNNGIVLI 487
            .:: |.||:.:|
Yeast   502 GIK-NANGVEII 512

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp110	NP_001189103.1	ASKHA_NBD_HSP70_HSPA4_like	4..378	CDD:466826	112/387 (29%)
SSZ1	NP_011931.2	ASKHA_NBD_HSP70_ScSsz1p-like	4..386	CDD:466830	113/390 (29%)