Protein Alignment Hsc70Cb and Hspa12a

DIOPT Version :9

• Sequence 1: NP_001189103.1
• Gene: Hsc70Cb / 39557
• FlyBaseID: FBgn0026418
• Length: 836
• Species: Drosophila melanogaster
• Sequence 2: XP_006527440.1
• Gene: Hspa12a / 73442
• MGIID: 1920692
• Length: 695
• Species: Mus musculus
• Alignment Length: 581
• Identity: 115/581 - (19%)
• Similarity: 191/581 - (32%)
• Gaps: 188/581 - (32%)

  Fly     3 VIGIDFGN-------------ESCYVAAARSGGIETLANDYSLRATPSFVAFDGKKRI--IGVAA 52
            |:.||||.             |..:|.....||...::|    :.||:.:....:::.  .|.||
Mouse    78 VVAIDFGTTSSGYAYSFTKEPECIHVMRRWEGGDPGVSN----QKTPTTILLTPERKFHSFGYAA 138

  Fly    53 KN----------QQVTNMKNTVGGFKRLLGRKFNDPHVQHELTSIPARVEARGDGSIGIKVNYLG 107
            ::          :|...::.    ||..|       |...:||.......|.|.     ||..|
Mouse   139 RDFYHDLDPSEAKQWLYLEK----FKMKL-------HTTGDLTMDTDLTAANGK-----KVKAL- 186

  Fly   108 EDQHFGPEQLTAMLFTKLKETSAAAMQTQVND--------CVIACPVFFTNAERKALLDAAQIAG 164
                    ::.|......||.:...:..|...        .||..|..:....::.:.:||..||
Mouse   187 --------EIFAYALQYFKEQALKELSDQAGSDFENSDVRWVITVPAIWKQPAKQFMREAAYQAG 243

  Fly   165 L----------------------NVLRL--MNETTATALAYGFYKNDLF--------EDKPRN-- 195
            |                      ..|||  |.|.::.|:..|:..:|..        |...||
Mouse   244 LASPENSEQLIIALEPEAASIYCRKLRLHQMIELSSKAVVNGYSASDTVGAGFAQAKEHVRRNRQ 308

  Fly   196 ----------------------VIFVDFGHSS--LQASACAFTKGKLKML-ASTWDQIGGRDIDL 235
                                  .:.||.|..:  |........:|.||.| .:|....|...:|.
Mouse   309 SRTFLVENVIGEIWSELEEGDKYVVVDSGGGTVDLTVHQIRLPEGHLKELYKATGGPYGSLGVDY 373

  Fly   236 ----ALGDYFAKEFQERYKINAKTNARANLRLLTEIEKLKKQMSANSTKLPLNIECFLDDID--- 293
                .|...|.::|.|::||.   ...|.:.|:...|..|:..:.:.|. ||||......||
Mouse   374 EFEKLLCKIFGEDFIEQFKIK---RPAAWVDLMIAFESRKRAAAPDRTN-PLNITLPFSFIDYYK 434

  Fly   294 ------VSSSMQRSQ------------------MEELCAPVLQRVEQTFKRLLAESKLQLDDIHS 334
                  |..::::|.                  |..|..|.:..:.:..:.|.  .|.::..:..
Mouse   435 KFRGHSVEHALRKSNVDFVKWSSQGMLRMSPDAMNALFKPTIDSIIEHLRDLF--QKPEVSTVKF 497

  Fly   335 VEIVGGSSRIPSVKQLIEQVFNKPASTTLNQDEAVS--RGAALQCAIMSPAV-RVRE----FGVT 392
            :.:|||.:..|.::|.::..|.......:.||..::  :||.|  ..:.||| :||.    :||.
Mouse   498 LFLVGGFAEAPLLQQAVQTAFGDKCRIIIPQDVGLTILKGAVL--FGLDPAVIKVRRSPLTYGVG 560

  Fly   393 DIQNYA------VKVL------W---------DSEGSAAPGEIEIFPQYHASPFSRLLTIN 432
            .:..|.      .|:|      |         .::.|.|.||:.......|.|...::.||
Mouse   561 VLNRYVEGKHPPEKLLVKDGTRWCTDVFDKFISADQSVALGELVKRSYTPAKPSQLVIIIN 621

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70Cb	NP_001189103.1	HSPA4_like_NDB	2..381	CDD:212670	96/502 (19%)
		HSP70	3..682	CDD:278441	115/581 (20%)
Hspa12a	XP_006527440.1	HSPA12A_like_NBD	77..543	CDD:212685	96/501 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900