Protein Alignment Hsc70Cb and HSPA13

DIOPT Version :9

• Sequence 1: NP_001189103.1
• Gene: Hsc70Cb / 39557
• FlyBaseID: FBgn0026418
• Length: 836
• Species: Drosophila melanogaster
• Sequence 2: NP_008879.3
• Gene: HSPA13 / 6782
• HGNCID: 11375
• Length: 471
• Species: Homo sapiens
• Alignment Length: 421
• Identity: 117/421 - (27%)
• Similarity: 198/421 - (47%)
• Gaps: 51/421 - (12%)

  Fly     3 VIGIDFGNESCYVAA--ARSGGIETLANDYSLRATPSFVAFDGKKRIIGVAAKNQQVTNMKNTVG 65
            |||||.|...|.|..  ..:|.::.:.::....:.||.|:|......:|..:.....:|.:||:.
Human    33 VIGIDLGTTYCSVGVFFPGTGKVKVIPDENGHISIPSMVSFTDNDVYVGYESVELADSNPQNTIY 97

  Fly    66 GFKRLLGRKFNDPHVQHELTSIPARVEARGDGSIGIKVNYLGEDQHFGPEQLTAMLFTKLKETSA 130
            ..||.:|:.|....::.|:...|.:| ...:|.:...|. ..|.....||.:.:.|..||||.:.
Human    98 DAKRFIGKIFTAEELEAEIGRYPFKV-LNKNGMVEFSVT-SNETITVSPEYVGSRLLLKLKEMAE 160

  Fly   131 AAMQTQVNDCVIACPVFFTNAERKALLDAAQIAGLNVLRLMNETTATALAYGFYKNDLFEDKPRN 195
            |.:...|.:.||:.|..|...:|.:.::||.:|||.:||::||.||.|:|||.:|.|:|     :
Human   161 AYLGMPVANAVISVPAEFDLKQRNSTIEAANLAGLKILRVINEPTAAAMAYGLHKADVF-----H 220

  Fly   196 VIFVDFGHSSLQASACAFTKGK-LKMLASTWDQIGGRDIDLALGDYFAKEFQERY---------- 249
            |:.:|.|..:|..|......|. |....|..:::||:|.:..|..|..|:..:.|
Human   221 VLVIDLGGGTLDVSLLNKQGGMFLTRAMSGNNKLGGQDFNQRLLQYLYKQIYQTYGFVPSRKEEI 285

  Fly   250 ----------KINAKTNARANLR-LLTEIEKLKKQMSANSTKLPLNIECFLDDIDVSS------- 296
                      |:|...:..|.|. |||..|:.:|:..::.|:||.:.....||..|:|
Human   286 HRLRQAVEMVKLNLTLHQSAQLSVLLTVEEQDRKEPHSSDTELPKDKLSSADDHRVNSGFGRGLS 350

  Fly   297 -------------SMQRSQMEELCAPVLQRVEQTFKRLLAESKLQLDDIHSVEIVGGSSRIPSVK 348
                         .:.|...:.|...:.|::....:::|.|..|:..:|..|.:||||:|||.::
Human   351 DKKSGESQVLFETEISRKLFDTLNEDLFQKILVPIQQVLKEGHLEKTEIDEVVLVGGSTRIPRIR 415

  Fly   349 QLIEQVFNKPASTTLNQDEAVSRGAALQCAI 379
            |:|::.|.|..:|:::.|.||..|.|:|..|
Human   416 QVIQEFFGKDPNTSVDPDLAVVTGVAIQAGI 446

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70Cb	NP_001189103.1	HSPA4_like_NDB	2..381	CDD:212670	117/421 (28%)
		HSP70	3..682	CDD:278441	117/421 (28%)
HSPA13	NP_008879.3	HSPA13-like_NBD	12..463	CDD:212679	117/421 (28%)
		PRK13930	32..442	CDD:237564	114/415 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	315..352		9/36 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900